CFI
-
Official Full Name
complement factor I
-
Overview
Complement factor I, also known as C3B/C4B inactivator, is a protein that in humans is encoded by the CFI gene. Complement Factor I (fI) is a protein of the complement system, first isolated in 1966 in guinea pig serum that regulates complement activation by cleaving cell-bound or fluid phase C3b and C4b. -
Synonyms
CFI; complement factor I; I factor (complement) , IF; C3b INA; C3b inactivator; FI; KAF; Konglutinogen activating factor; C3b-inactivator; C3B/C4B inactivator; complement component I; light chain of factor I; Konglutinogen-activating factor; complement fa;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mammalian cell
- Mammalian Cell
- Mammalian cells
- Normal human serum (shown by certified tests to be negative for HBsAg, HTLV-I/II, STS and for antibodies to HCV, HIV-1 and HIV-II)
- Flag
- His
- His (Fc)
- Avi
- Myc
- His|GST
- MYC
- DDK
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | CFI-290H | Recombinant Human CFI protein, His-tagged | E.coli | His | Ile340~Val583 | |
Human | CFI-9302H | Recombinant Human CFI protein, His-tagged | E.coli | His | Leu28~Gly243 | |
Human | CFI-2054H | Recombinant Human CFI protein, His & GST-tagged | E.coli | His/GST | Leu28~Gly243 (Accession # P05156) | |
Human | CFI-7556HCL | Recombinant Human CFI 293 Cell Lysate | HEK293 | N/A | ||
Human | CFI-1051H | Recombinant Human CFI Protein (Lys19-Ile335), N-His tagged | E.coli | N-His | Lys19-Ile335 | |
Human | CFI-105H | Active Native Human Factor I | Normal human serum (shown by certified tests to be negative for HBsAg, HTLV-I/II, STS and for antibodies to HCV, HIV-1 and HIV-II) | N/A | ||
Human | CFI-1531HFL | Recombinant Full Length Human CFI Protein, C-Flag-tagged | Mammalian cells | Flag | ||
Human | CFI-585H | Recombinant Human CFI Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | CFI-585H-B | Recombinant Human CFI Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Cfi-2055M | Recombinant Mouse Cfi protein, His-tagged | E.coli | His | Arg358~Val603 | |
Mouse | CFI-3349M | Recombinant Mouse CFI Protein | Mammalian Cell | His | ||
Mouse | Cfi-880M | Recombinant Mouse Cfi Protein, MYC/DDK-tagged | HEK293T | MYC/DDK | ||
Mouse | Cfi-2210M | Recombinant Mouse Cfi protein, His&Myc-tagged | Insect Cell | His&Myc | 19-603aa | |
Mouse | CFI-1613M | Recombinant Mouse CFI Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | Cfi-938M | Recombinant Mouse Cfi protein, His&Myc-tagged | Mammalian cell | His&Myc | 19-603aa | |
Mouse | CFI-1613M-B | Recombinant Mouse CFI Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Cfi-1070M | Recombinant Mouse Cfi protein, His&Myc-tagged | HEK293 | His&Myc | 19-603aa | |
Rat | CFI-1355R | Recombinant Rat CFI Protein | Mammalian Cell | His | ||
Rat | Cfi-4998R | Recombinant Rat Cfi protein, His&Myc-tagged | HEK293 | His&Myc | 19-604aa | |
Rat | CFI-1013R | Recombinant Rat CFI Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | Cfi-2211R | Recombinant Rat Cfi protein, His&Myc-tagged | Insect Cell | His&Myc | 19-604aa | |
Rat | CFI-1013R-B | Recombinant Rat CFI Protein Pre-coupled Magnetic Beads | HEK293 | |||
Chicken | CFI-4700C | Recombinant Chicken CFI | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- CFI Related Articles
CFI involved in several pathways and played different roles in them. We selected most pathways CFI participated on our site, such as Complement and coagulation cascades, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with CFI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Complement and coagulation cascades | C5AR1;PLG;F2;Serpina1b;SERPINF2;F3;F5;SERPINE1;SERPINA1D |
Staphylococcus aureus infection | HLA-DRA;C1QB;C1S;MBL1;FCGR2C;FCGR1A;ITGAM;MBL2;FPR2 |
CFI has several biochemical functions, for example, metal ion binding, protein binding, scavenger receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CFI itself. We selected most functions CFI had, and list some proteins which have the same functions with CFI. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
metal ion binding | EXT1C;EGR3;DGKAA;MTHFS;CCDC71L;ZSCAN20;GNAZ;GTF2E1;ESR2B |
protein binding | NOL4;C8orf48;NKX3-1;PEX16;LRRK2;VHL;SP100;LRGUK;PKP2 |
scavenger receptor activity | TMPRSS4;PRSS12;PRG4B;CD5L;TMPRSS15;CD5;CCBP2;LOXL3A;ENPP2 |
serine-type endopeptidase activity | PLAT;ST14;KLK1B16;PRSS59.2;HTRA4;CFB;KLK14;KEX2;CTSC |
CFI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CFI here. Most of them are supplied by our site. Hope this information will be useful for your research of CFI.
f_hcvh
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All CFI Products
Required fields are marked with *
My Review for All CFI Products
Required fields are marked with *