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CHAF1B

Official Full Name

chromatin assembly factor 1, subunit B (p60)
Overview

Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
Synonyms

CHAF1B; chromatin assembly factor 1, subunit B (p60); chromatin assembly factor 1 subunit B; CAF 1; CAF1; CAF1A; CAF1P60; Chromatin assembly factor I; p60 subunit; human chromatin assembly factor I p60 subunit; M phase phosphoprotein 7; MPHOSPH7; MPP7; CA;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

Flag
GST
His
His (Fc)
Avi
His|T7
MYC
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CHAF1B-1204H	Recombinant Human CHAF1B Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CHAF1B-7547HCL	Recombinant Human CHAF1B 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CHAF1B-1205H	Recombinant Human CHAF1B protein, Myc/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	CHAF1B-591H	Recombinant Human CHAF1B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	CHAF1B-3309HF	Recombinant Full Length Human CHAF1B Protein, GST-tagged	In Vitro Cell Free System	GST	559 amino acids	Inquiry
Human	CHAF1B-51HFL	Recombinant Full Length Human CHAF1B Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	CHAF1B-591H-B	Recombinant Human CHAF1B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Chaf1b-1675M	Recombinant Mouse Chaf1b protein, His & T7-tagged	E.coli	His/T7	Met1~Asn199 (Accession # Q9D0N7)	Inquiry
Mouse	Chaf1b-482M	Recombinant Mouse Chaf1b Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Zebrafish	CHAF1B-12253Z	Recombinant Zebrafish CHAF1B	Mammalian Cell	His		Inquiry
Chicken	CHAF1B-1862C	Recombinant Chicken CHAF1B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CHAF1B involved in several pathways and played different roles in them. We selected most pathways CHAF1B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHAF1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CHAF1B has several biochemical functions, for example, chromatin binding, histone binding, unfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHAF1B itself. We selected most functions CHAF1B had, and list some proteins which have the same functions with CHAF1B. You can find most of the proteins on our site.

Function	Related Protein
chromatin binding	BAHD1;SOX10;GATA2B;FEZF2;TOX4;ESR1;UPF1;TLE1;SMARCD1
histone binding	H3F3B;UHRF2;HIST1H3G;PRKCB;HIST1H3H;HIST1H4I;HIST1H4D;SPTY2D1;CD1D
unfolded protein binding	ST13;H2-KE2;CRYABB;AFG3L2;SPG7;CCT2;CRYAA;TUBB4B;HSPA1B

CHAF1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHAF1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CHAF1B.

HIST1H3D; CHAF1A; CBX5; env; CNOT6L; ASF1B; Aff1; h3-catd; MYC; env