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CHMP4C

  • Official Full Name

    CHMP4C charged multivesicular body protein 4C [ Homo sapiens ]

  • Overview

    CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
  • Synonyms

    Charged multivesicular body protein 4c; CHM4C_HUMAN; CHMP4c; Chromatin-modifying protein 4c; hSnf7-3; hVps32-3; SNF7 homolog associated with Alix 3; SNF7-3; Vacuolar protein sorting-associated protein 32-3; Vps32-3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHMP4C-11188H Recombinant Human CHMP4C, His-tagged E.coli His 1-233a.a.
Human CHMP4C-7531HCL Recombinant Human CHMP4C 293 Cell Lysate HEK293 N/A
Human CHMP4C-602H Recombinant Human CHMP4C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CHMP4C-1711HFL Recombinant Full Length Human CHMP4C Protein, C-Flag-tagged Mammalian cells Flag
Human CHMP4C-602H-B Recombinant Human CHMP4C Protein Pre-coupled Magnetic Beads HEK293
Mouse CHMP4C-3409M Recombinant Mouse CHMP4C Protein Mammalian Cell His
Mouse CHMP4C-1654M Recombinant Mouse CHMP4C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Chmp4c-2150M Recombinant Mouse Chmp4c Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CHMP4C-1654M-B Recombinant Mouse CHMP4C Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CHMP4C-851R Recombinant Rhesus monkey CHMP4C Protein, His-tagged Mammalian Cell His
Rhesus Macaque CHMP4C-677R-B Recombinant Rhesus Macaque CHMP4C Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CHMP4C-677R Recombinant Rhesus Macaque CHMP4C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CHMP4C-2568Z Recombinant Zebrafish CHMP4C Mammalian Cell His
Chicken CHMP4C-4331C Recombinant Chicken CHMP4C Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CHMP4C involved in several pathways and played different roles in them. We selected most pathways CHMP4C participated on our site, such as Budding and maturation of HIV virion, Cellular responses to stress, Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHMP4C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Budding and maturation of HIV viriongag;PPIA;CHMP4B;VPS37A;CHMP4C;PDCD6IP
Cellular responses to stressRING1;HMGA1;HIST1H1B;CBX8B;RAD50;RRAGB;WDR45L;DNAJB6;Txn1
DiseaseCDK8;AP1G1;HEYL;HMGA1;CCNC;MYO18A;KREMEN1;MMAA;SYT2
EndocytosisGRK5;CHMP2A;ARF3B;GIT2;CHMP4C;VPS35;RAB11FIP5;ARFGEF2;CAV3
Endosomal Sorting Complex Required For Transport (ESCRT)CHMP4C;CHMP4B;STAM2;SNF8;VPS37A
HIV InfectionPACS1;PSTPIP2;PPIAL4A;CHMP4C;AP1G1;TAF1L;PDCD6IP;TCEB3;CDK9
HIV Life CycleSSRP1;CHMP4C;CHMP4B;PSTPIP2;ELL;PSIP1;PDCD6IP;RCC1;NMT1
Infectious diseaseKPNA4;CHMP4B;SYT2;IPO5;EEF2;KPNA5;RCC1;NMT1;AP1S1

CHMP4C has several biochemical functions, for example, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHMP4C itself. We selected most functions CHMP4C had, and list some proteins which have the same functions with CHMP4C. You can find most of the proteins on our site.

Function Related Protein
protein bindingCAMP;HIPK4;KRT15;SPATA8;ASF1A;RALGAPA1;KRTAP19-5;DICER1;HIST1H4L
protein homodimerization activityHSD17B4;GNPTG;MTUS2;ADIPOQ;SHMT1;CEACAM5;TP53I3;SMAD2;KLHL7

CHMP4C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHMP4C here. Most of them are supplied by our site. Hope this information will be useful for your research of CHMP4C.

USP8; 128872; USP54; STAMBP; PDCD6IP; IGHA1

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