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CHRNE

  • Official Full Name

    cholinergic receptor, nicotinic, epsilon

  • Overview

    Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
  • Synonyms

    CHRNE; cholinergic receptor, nicotinic, epsilon; cholinergic receptor, nicotinic, epsilon polypeptide; acetylcholine receptor subunit epsilon; ACHRE; ACHE_HUMAN; AchR epsilon subunit; CMS1D; CMS1E; CMS2A; FCCMS; SCCMS;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Xenopus laevis (African clawed frog)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHRNE-1293H Recombinant Human CHRNE Protein, GST-Tagged Wheat Germ GST
Human CHRNE-29131TH Recombinant Human CHRNE Wheat Germ N/A 110 amino acids
Mouse CHRNE-3442M Recombinant Mouse CHRNE Protein Mammalian Cell His
Mouse Chrne-7895M Recombinant Mouse Chrne protein, His & T7-tagged E.coli His/T7 Lys21~Lys239 (Accession # P20782)
Mouse CHRNE-1671M Recombinant Mouse CHRNE Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CHRNE-1671M-B Recombinant Mouse CHRNE Protein Pre-coupled Magnetic Beads HEK293
Rat Chrne-3057R Recombinant Rat Chrne, His-tagged E.Coli or Yeast His 494
Rat CHRNE-1401R Recombinant Rat CHRNE Protein Mammalian Cell His
Rat CHRNE-1059R-B Recombinant Rat CHRNE Protein Pre-coupled Magnetic Beads HEK293
Rat CHRNE-1059R Recombinant Rat CHRNE Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL872BF Recombinant Full Length Bovine Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged E.coli expression system His Full Length (21-491)
Homo sapiens (Human) RFL27102HF Recombinant Full Length Human Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged E.coli expression system His Full Length (21-493)
Mus musculus (Mouse) RFL32653MF Recombinant Full Length Mouse Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged E.coli expression system His Full Length (21-493)
Rattus norvegicus (Rat) RFL27962RF Recombinant Full Length Rat Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged E.coli expression system His Full Length (21-494)
Xenopus laevis (African clawed frog) RFL7869XF Recombinant Full Length Xenopus Laevis Acetylcholine Receptor Subunit Epsilon(Chrne) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-504)
Zebrafish CHRNE-1106Z Recombinant Zebrafish CHRNE Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CHRNE involved in several pathways and played different roles in them. We selected most pathways CHRNE participated on our site, such as Acetylcholine Binding And Downstream Events, Activation of Nicotinic Acetylcholine Receptors, ErbB2/ErbB3 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Acetylcholine Binding And Downstream EventsCHRNA7;CHRNA2;CHRNB4;CHRNA5;CHRND;CHRNA3;CHRNE;CHRNB2;CHRNA4
Activation of Nicotinic Acetylcholine ReceptorsCHRNA2;CHRNA1;CHRND;CHRNA4;CHRNE;CHRNB2;CHRNB4;CHRNA5;CHRNA7
ErbB2/ErbB3 signaling eventsRNF41;FMNL3;CHRNA1;DOCK7;CHRNE
Highly sodium permeable acetylcholine nicotinic receptorsCHRNE;CHRNA3;CHRNB2;CHRNB4;CHRND;CHRNA4
Neuroactive ligand-receptor interactionDRD4B;TAAR64;NMBR;LPAR4;PRSS1;TAAR13D;OPRM1;P2RX7;GPR50
Neuronal SystemKCNA2;CHRNB2;CHRNA3;KCNQ2A;CHRND;SLC6A11;SLC1A3B;LIN7C;DDX1
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellCAMKK1B;NCALDA;NSFB;CHRNA2;CHRNE;CHRND;MYO6;GABRR2A;GRIP1
Postsynaptic nicotinic acetylcholine receptorsCHRNE;CHRNA2;CHRND

CHRNE has several biochemical functions, for example, contributes_to acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNE itself. We selected most functions CHRNE had, and list some proteins which have the same functions with CHRNE. You can find most of the proteins on our site.

Function Related Protein
contributes_to acetylcholine bindingCHRNA9;CHRNA5;CHRNE;CHRNB3B;CHRNA1;CHRNA2A;CHRND;CHRNB3A;CHRNA4B
acetylcholine receptor activityCHRNA7;ANXA9;CHRNA5;CHRNB4;CHRNA6;CHRNE;CHRNA4;CHRNA3;CHRNB2
acetylcholine-activated cation-selective channel activityCHRNA10A;CHRNA5;CHRNB3B;CHRNA4;CHRNA6;CHRNB3A;CHRNA2A;CHRNB2;CHRNE
cation transmembrane transporter activitySLC41A2;SLC41A1;SLC41A3;SLC30A7;SLC30A9;SLC30A1A;SLC30A1B;SLC30A5;SLC30A10

CHRNE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNE here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNE.

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