CLEC1B
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Official Full Name
C-type lectin domain family 1, member b
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Overview
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM;602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and;either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in;myeloid cells and NK cells (Colonna et al., 2000 (PubMed 10671229)). -
Synonyms
CLEC1B; C-type lectin domain family 1, member b; C-type lectin domain family 1 member B; 1810061I13Rik; C type lectin domain family 1 member B; C type lectin like receptor 2; C-type lectin-like receptor 2; C-type lectin-like receptor-2; CLC1B_HUMAN; CLEC 2; CLEC 2B; CLEC-2; CLEC2; CLEC2B; PRO1384; QDED721; OTTMUSP00000033486; OTTMUSP00000033487;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Rabbit
- Wheat Germ
- Fc
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CLEC1B Related Articles
- CLEC1B Related Research Area
CLEC1B involved in several pathways and played different roles in them. We selected most pathways CLEC1B participated on our site, such as GPVI-mediated activation cascade, Hemostasis, Platelet activation, signaling and aggregation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GPVI-mediated activation cascade | RHOGA;LCP2A;RHOB;CLEC1B;FCER1GL;PIK3R6;PDPN;C6orf25;G6b |
| Hemostasis | CFHL4;PROCA;CFHL1;APOA1B;JAM2B;TREM1;SERPINF2B;CD9B;G6b |
| Platelet activation, signaling and aggregation | RHOGA;TFA;SCG3;F13A1B;FCER1GL;STXBP3;CLEC1B;TRPC6A;GNA13B |
CLEC1B has several biochemical functions, for example, carbohydrate binding, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC1B itself. We selected most functions CLEC1B had, and list some proteins which have the same functions with CLEC1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | GCKR;SBP;VCAN;Clec4n;Siglec1;MAN2C1;LGALS9L1;NOMO1;GANC |
| protein binding | C2orf28;EMX2;RABGEF1;SMAD5;SH3GLB1;HAND1;CSF2;CD14;KRT20 |
| transmembrane signaling receptor activity | CD69;TNFRSF10C;ERBB2;TLR4;TLR2-2;CD5;CLDN4;FZD7B;Fzd4 |
CLEC1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC1B.
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