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COLQ

  • Official Full Name

    collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

  • Overview

    This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    COLQ; collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; acetylcholinesterase collagenic tail peptide; acetylcholinesterase associated collagen; AChE Q subunit; collagenic tail of endplate acetylcholinesterase; EAD; single strand of homotrimeric collagen like tail subunit of asymmetric acetylcholinesterase; Acetylcholinesterase collagen-like tail subunit isoform I; Acetylcholinesterase collagenic tail peptide precursor; Acetylcholinesterase-associated collagen; asymmetric acetylcholinesterase; COLQ_HUMAN; single strand of homotrimeric collagen-like tail subunit of asymmetric acetylcholinesterase;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human COLQ-1672H Recombinant Human COLQ Protein, GST-tagged Wheat Germ GST
Human COLQ-2212HF Recombinant Full Length Human COLQ Protein, GST-tagged In Vitro Cell Free System GST 445 amino acids
Mouse COLQ-3759M Recombinant Mouse COLQ Protein Mammalian Cell His
Mouse COLQ-1875M Recombinant Mouse COLQ Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse COLQ-1875M-B Recombinant Mouse COLQ Protein Pre-coupled Magnetic Beads HEK293
Rat COLQ-1525R Recombinant Rat COLQ Protein Mammalian Cell His
Rat Colq-3061R Recombinant Rat Colq, His-tagged E.Coli or Yeast His 458
Rat COLQ-1182R-B Recombinant Rat COLQ Protein Pre-coupled Magnetic Beads HEK293
Rat COLQ-1182R Recombinant Rat COLQ Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • COLQ Related Articles
  • COLQ Related Research Area

COLQ involved in several pathways and played different roles in them. We selected most pathways COLQ participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with COLQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

COLQ has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COLQ itself. We selected most functions COLQ had, and list some proteins which have the same functions with COLQ. You can find most of the proteins on our site.

Function Related Protein
protein bindingDARS2;DOK2;NUBP1;PLCG2;FGF2;ENO1;NGFR;HSPG2;RNF144B

COLQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COLQ here. Most of them are supplied by our site. Hope this information will be useful for your research of COLQ.

Katarzyna, MZ; Belaya, K; et al. Collagen Q - A potential target for autoantibodies in myasthenia gravis. JOURNAL OF THE NEUROLOGICAL SCIENCES 348:241-244(2015).
Ohno, K; Ito, M; et al. Collagen Q is a Key Player for Developing Rational Therapy for Congenital Myasthenia and for Dissecting the Mechanisms of Anti-MuSK Myasthenia Gravis. JOURNAL OF MOLECULAR NEUROSCIENCE 53:359-361(2014).
  • Q&As
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