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UQCRC2

  • Official Full Name

    ubiquinol-cytochrome c reductase core protein II

  • Overview

    Ubiquinol-cytochrome c reductase core protein II is a protein that in humans is encoded by the UQCRC2 gene. Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), whi
  • Synonyms

    UQCRC2; ubiquinol-cytochrome c reductase core protein II; cytochrome b-c1 complex subunit 2, mitochondrial; QCR2; UQCR2; mitochondrial; Complex III subunit 2; Core protein II; Cytochrome b-c1 complex subunit 2; EC 1.10.2.2; QCR2_HUMAN; Ubiquinol cytochrome c reductase complex core protein 2 mitochondrial; Ubiquinol cytochrome c reductase core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
  • T7
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • UQCRC2 Related Articles

UQCRC2 involved in several pathways and played different roles in them. We selected most pathways UQCRC2 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UQCRC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationATP6V0A4;ATP6V1D;ATP5S;UQCRB;NDUFAB1A;MT-ND4;SDHB;ATP5I;NDUFB3
Metabolic pathwaysCOX17;ATP5G3A;CEL.1;IMPA2;B3GNT3;FBP1A;ALG14;PIGYL;NOS2A
Cardiac muscle contractionACTC1B;UQCR11;ATP1B3B;CACNA1SB;CACNG1A;COX7A1;COX7C;ATP1B1A;CACNA1DA
Non-alcoholic fatty liver disease (NAFLD)PRKAG3;COX7B;RAC1;NDUFS4;NDUFB10;MAP3K5;UQCRC2;NDUFS3;PKLR
Alzheimers diseaseFADD;NDUFV1;NDUFA6;ATP2A1;CAPN1;NDUFV3;FAS;PSEN2;NDUFS7
Parkinsons diseaseNDUFAB1;NDUFS2;SDHB;PRKACB;ATP5G3;MT-ATP6;LRRK2;PRKACG;UBB
Huntingtons diseaseATP5E;UQCR10;COX6B1;NDUFA4;EP300;NDUFA9;NDUFV2;NDUFB2;DNAH6

UQCRC2 has several biochemical functions, for example, metalloendopeptidase activity, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UQCRC2 itself. We selected most functions UQCRC2 had, and list some proteins which have the same functions with UQCRC2. You can find most of the proteins on our site.

Function Related Protein
metalloendopeptidase activityMMP12;ADAM15;TLL1;YME1L1B;ADAM2;ADAM22;MMP14B;C6AST1;ECEL1
protein bindingGLP1R;TICAM1;AKAP12;SYNDIG1;STK38L;MEF2D;RIPPLY1;SUMO2;UNC119B
protein complex bindingPRMT5;BRK1;ATG101;MAPK8IP2;THRA;COG2;YWHAB;FADD;OTOF
zinc ion bindingDTNA;RNF5;GFI1;ADAT2;UHRF2;ZNF385B;EWSR1A;ADAMTS4;LMX1B

UQCRC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UQCRC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UQCRC2.

UQCRC1; CACNA1A; a8k1f4_human; HLA-B; ARF6; 15-deoxy-delta(12,14; RNH1; ATF2; Csk; HTT; ICT1; Ddb1; Rmdn3; P; HUWE1; Ercc6l; SLX1A

Hu, WH; Hausmann, ON; et al. Identification and characterization of a novel Nogo-interacting mitochondrial protein (NIMP). JOURNAL OF NEUROCHEMISTRY 81:36-45(2002).
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