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CORO1A

  • Official Full Name

    coronin, actin binding protein, 1A

  • Overview

    This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
  • Synonyms

    CORO1A; coronin, actin binding protein, 1A; coronin-1A; Clabp TACO; coronin 1; HCORO1; p57; clipin-A; coronin-1; coronin-like protein A; coronin-like protein p57; tryptophan aspartate-containing coat protein; TACO; CLABP; CLIPINA; FLJ41407; MGC117380;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CORO1A-1723H Recombinant Human CORO1A Protein, GST-tagged Wheat Germ GST
Human CORO1A-7345HCL Recombinant Human CORO1A 293 Cell Lysate HEK293 N/A
Human CORO1A-1668H Recombinant Human CORO1A protein, His & T7-tagged E.coli His/T7 Arg7~Glu204 (Accession # P31146)
Human CORO1A-645H Recombinant Human CORO1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CORO1A-1487HFL Recombinant Full Length Human CORO1A Protein, C-Flag-tagged Mammalian cells Flag
Human CORO1A-645H-B Recombinant Human CORO1A Protein Pre-coupled Magnetic Beads HEK293
Human CORO1A-1715H Recombinant Human CORO1A Protein (Arg7-Glu204), N-His tagged E.coli N-His Arg7-Glu204
Mouse CORO1A-3797M Recombinant Mouse CORO1A Protein Mammalian Cell His
Mouse CORO1A-1903M Recombinant Mouse CORO1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CORO1A-1903M-B Recombinant Mouse CORO1A Protein Pre-coupled Magnetic Beads HEK293
Mouse Coro1a-898M Recombinant Mouse Coro1a Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CORO1A-1545R Recombinant Rat CORO1A Protein Mammalian Cell His
Rat CORO1A-1202R-B Recombinant Rat CORO1A Protein Pre-coupled Magnetic Beads HEK293
Rat Coro1a-1669R Recombinant Rat Coro1a protein, His & T7-tagged E.coli His/T7 Met1~Glu204 (Accession # Q91ZN1)
Rat CORO1A-1202R Recombinant Rat CORO1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CORO1A-11336Z Recombinant Zebrafish CORO1A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CORO1A Related Articles

CORO1A involved in several pathways and played different roles in them. We selected most pathways CORO1A participated on our site, such as Phagosome, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CORO1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhagosomeFCGR3B;TUBA8L3;cgr2b;TAP1;MRC2;HLA-A;RAB5AB;ATP6V0A4;ATP6V0A2
TuberculosisTRAF6;ITGB2;IFNA4;FCGR3B;RAB5C;MAPK1;FADD;HLA-DRB3;IRAK1

CORO1A has several biochemical functions, for example, actin binding, actin filament binding, actin monomer binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CORO1A itself. We selected most functions CORO1A had, and list some proteins which have the same functions with CORO1A. You can find most of the proteins on our site.

Function Related Protein
actin bindingVCL;MYO10;ARPC5L;NEXN;FXYD5;TNNT2A;WHAMM;SYNPO2L;SNTA1
actin filament bindingESPN;TULP1;ANXA8;TTN;PLS1;ACTN2B;CAPZB;CTNNA2;SYNE2
actin monomer bindingLIMA1;LMOD3;PFN1;TWF1;TMSB;MTSS1;PRKCE;TWF2;CORO1A
cytoskeletal protein bindingANXA2B;FRMD5;FLNC;PACSIN3;DES;CAPN10;NCKIPSD;EZRA;ANXA2
myosin heavy chain bindingMYL9;MYL12B;PDLIM2;MYL2;AMPD1;MYBPC3;CORO1A
phosphatidylinositol 3-kinase bindingINSRA;IGF1R;BECN1;HCST;IGF1RB;INSRB;IGF1RA;LCK;DAB1
poly(A) RNA bindingDKC1;CAPRIN1;NOL11;PCSK9;EIF4E2;SFRS9;RPL35;KHDRBS3;PRPF6
protein C-terminus bindingCDC20;HSPB7;KCNIP3;CEP135;PPP2CA;VPS4B;MIF4GD;VPS36;PIAS4
protein bindingAPOBEC2B;IST1;GSN;POT1A;Shh;RNF24;PIAS3;DOCK9;PCSK5
protein homodimerization activityAOC3;CTBP1;PRKG2;MFF;GRIK2;MYOM3;CCBL2;CARS;ACTN1

CORO1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CORO1A here. Most of them are supplied by our site. Hope this information will be useful for your research of CORO1A.

FSD2; GOLGA2; STAT3; DKK1; UBE2G2; POLR1C; LMO2; MAGOH; SMAD3; FHL3; GIT2; TAB1; tuf; glpA; spoVR

Xu, XJ; Tang, YM; et al. ZCH-2B8a, an antibody targeting actin-binding protein coronin-1a, is a potential therapeutic agent for B-lineage malignancies. JOURNAL OF DRUG TARGETING 22:488-497(2014).
Eitzen, G; Lo, AN; et al. Proteomic analysis of secretagogue-stimulated neutrophils implicates a role for actin and actin-interacting proteins in Rac2-mediated granule exocytosis. PROTEOME SCIENCE 9:-(2011).
Ahmed, Z; Shaw, G; et al. Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 55:687-700(2007).
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