CSF2RA
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Official Full Name
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
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Overview
CD116 is a 70-85 kD alpha chain of the GM-CSF receptor. It combines with CDw131 beta chain to form the high affinity GM-CSF receptor. A soluble form of CD116, which binds GM-CSF with a relatively low affinity, has been identified. In addition, an alternat -
Synonyms
CSF2RA; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; GM-CSFRalpha; GMCSFR-alpha; GM-CSF-R-alpha; colony stimulating factor 2 receptor alpha chain; CD116; Csfgmra; GM-CSFR; GM-CSF-Ra;
- Recombinant Proteins
- Cell & Tissue Lysates
- Recombinant Antibodies
- Antibody
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Rhesus monkey
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Mammalian cells
- Rat
- Wheat Germ
- Biotin
- C
- hFc
- His
- GST
- hIgG1
- hIgG4
- His (Fc)
- Avi
- His|GST
- SUMO
- human|IgG1|Fc
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CSF2RA Related Research Area
CSF2RA involved in several pathways and played different roles in them. We selected most pathways CSF2RA participated on our site, such as ARMS-mediated activation, Axon guidance, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF2RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ARMS-mediated activation | HBEGF;KBTBD7;CNKSR1;DLG4;NRG2A;CSF2;DUSP1;SLC14A2;FGF8B |
| Axon guidance | DUSP10;PAK3;NEFLB;RHOAE;EPHB4A;RHOD;GFRA2;ACTR2B;FES |
| Cytokine Signaling in Immune system | CASPB;EIF4G1;GHRB;GBP4;PELI2;EDA;JAK1;RASGRP4;FGF8B |
| Cytokine-cytokine receptor interaction | CXCL2;TNFRSF9;CCR8L;CXCR5;Pdgfa&Pdgfb;TNFRSF4;IL17A;IL6;IL12BA |
| DAP12 interactions | JAK3;TRAT1;SPTB;TREM1;MOV10;FRS3;SIGLEC15;PEBP1;NRG3 |
| DAP12 signaling | FGF8B;FRS2A;FRS2B;KBTBD7;CSF2RA;AGO3;NRG2A;DUSP7;RASGEF1A |
| Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4) | SFTPC;CSF2RA;CSF2RB;SFTPB |
| Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) | SFTPB;SFTPC;CSF2RA |
CSF2RA has several biochemical functions, for example, granulocyte colony-stimulating factor binding, granulocyte colony-stimulating factor receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF2RA itself. We selected most functions CSF2RA had, and list some proteins which have the same functions with CSF2RA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| granulocyte colony-stimulating factor binding | |
| granulocyte colony-stimulating factor receptor activity | |
| protein binding | ACTB;MEOX2;ZRANB1;CDKN3;TMUB2;MYOZ2;PKM2;YES1;PRH1 |
| receptor activity | VMN1R46;VMN1R50;Siglece;SEMA4D;CD1D;ADIPOR2;PVR;P2RY11;ADCYAP1R1 |
CSF2RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF2RA here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF2RA.
FATE1; IKBKB; CSF2; KIT; PIK3R1
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