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CTNNA2

  • Official Full Name

    catenin (cadherin-associated protein), alpha 2

  • Overview

    May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation.
  • Synonyms

    CTNNA2; catenin (cadherin-associated protein), alpha 2; catenin alpha-2; cadherin associated protein; related; cancer/testis antigen 114; CAP R; CT114; Alpha catenin related protein; Alpha N Catenin; Cadherin Associated Protein Related; CAPR; Catenin (cadherin associated protein) alpha 2; Catenin alpha 2; CTNN A2; CTNR; DKFZp686H02198; alpha N-catenin; alpha-N-catenin; OTTHUMP00000216460; OTTHUMP00000216461; OTTHUMP00000216462; alpha-catenin-related protein; cadherin-associated protein, related; CAP-R;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CTNNA2-2078H Recombinant Human CTNNA2 Protein, GST-tagged Wheat Germ GST
Human CTNNA2-11670H Recombinant Human CTNNA2, GST-tagged E.coli GST 1-350a.a.
Human CTNNA2-27148TH Recombinant Human CTNNA2, His-tagged E.coli His
Human CTNNA2-7202HCL Recombinant Human CTNNA2 293 Cell Lysate HEK293 N/A
Human CTNNA2-984H Recombinant Human CTNNA2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CTNNA2-2306HF Recombinant Full Length Human CTNNA2 Protein, GST-tagged In Vitro Cell Free System GST 905 amino acids
Mouse CTNNA2-4029M Recombinant Mouse CTNNA2 Protein Mammalian Cell His
Mouse Ctnna2-778M Recombinant Mouse Ctnna2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CTNNA2-2056M Recombinant Mouse CTNNA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CTNNA2-2056M-B Recombinant Mouse CTNNA2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CTNNA2-1079R Recombinant Rhesus monkey CTNNA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CTNNA2-904R Recombinant Rhesus Macaque CTNNA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CTNNA2-904R-B Recombinant Rhesus Macaque CTNNA2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CTNNA2-7412Z Recombinant Zebrafish CTNNA2 Mammalian Cell His
Chicken CTNNA2-6693C Recombinant Chicken CTNNA2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CTNNA2 involved in several pathways and played different roles in them. We selected most pathways CTNNA2 participated on our site, such as Adherens junction, Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy (ARVC), which may be useful for your reference. Also, other proteins which involved in the same pathway with CTNNA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adherens junctionWASF2;INSRB;MAPK3;CDC42L2;SSX2IPA;CDC42;BAIAP2A;MAP3K7;INSRA
Arrhythmogenic right ventricular cardiomyopathyCACNG2;DAG1;CDH2;DSP;JUP;DSG2;DMD;DES;CTNNA1
Arrhythmogenic right ventricular cardiomyopathy (ARVC)CACNB3;ACTN2;DMD;RYR2;ITGA10;ITGB5;CACNB4;GJA1;ITGA6
Bacterial invasion of epithelial cellsPTK2;ILK;CD2AP;PXN;CLTA;SHC1;WASF1;SEPT11;SHC4
CDO in myogenesisMYOG;BNIP2;SPAG9;BOC;CDON;MYOD1;TCF12;CTNNA2;CDH2
Developmental BiologyEFNB3;CLTA;MEF2AA;CLASP1;CHL1;MED18;LGI3;CSNK2B;LGI1A
Endometrial cancerTCF7L2;ARAF;PIK3CA;MLH1;MAP2K2;SOS1;HRAS;MAP2K1;CTNNA2
Hippo signaling pathwayTCF7L2;BMP2;CCND1;WNT7A;GDF6;BMP6;TP73;RASSF1;MOB1A

CTNNA2 has several biochemical functions, for example, actin filament binding, cadherin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTNNA2 itself. We selected most functions CTNNA2 had, and list some proteins which have the same functions with CTNNA2. You can find most of the proteins on our site.

Function Related Protein
actin filament bindingSMYHC2;LASP1;NEXN;VPS16;CTNNAL1;GAS2L2;TMOD1;ADD1;MYH11
cadherin bindingNDRG1;CD2AP;PROM1;CTNNA2;JUPA;CTNND1;CTNNB1;P2RX4;TRPC4
protein bindingTNFSF10;TSGA10;FAM72A;PHYHIPL;FAM96B;MLLT3;CDKN2A;SPOP;MPZL3
structural constituent of cytoskeletonCYLC1;ACTA1;TUBA3E;VILL;CYLC2;COX4I2;ARPC5;EPB42;EPB41

CTNNA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTNNA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTNNA2.

JUP; EGFR; YAP1; ESR2

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