cxcl10
Share
  • Official Full Name
  • chemokine (C-X-C motif) ligand 10
  • Background
  • This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Jul 2008]
  • Synonyms
  • CXCL10; chemokine (C-X-C motif) ligand 10; C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10; C-X-C motif chemokine 10; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10;
Cat.#:CXCL10-805MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse CXCL10 Protein (Ile22-Pro98), His-tagged
+Inquiry
Cat.#:CXCL10-938RTag:His
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat CXCL10 Protein (Ile22-Pro98), His-tagged
+Inquiry
Cat.#:CXCL10-2158HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CXCL10 Protein, GST-tagged
+Inquiry
Cat.#:CXCL10-1176RTag:
Source (Host):E. coliSpecies:Rhesus monkey
Product nameRecombinant Rhesus Monkey CXCL10 Protein
+Inquiry
Cat.#:CXCL10-4341DTag:
Source (Host):YeastSpecies:Dolphin
Product nameRecombinant Dolphin CXCL10 Protein
+Inquiry
Cat.#:CXCL10-4342CTag:
Source (Host):YeastSpecies:Caprine
Product nameRecombinant Caprine CXCL10 Protein
+Inquiry
Cat.#:Cxcl10-4347GTag:
Source (Host):YeastSpecies:Guinea Pig
Product nameRecombinant Guinea Pig Cxcl10 Protein
+Inquiry
Cat.#:CXCL10-025HTag:Fc/His
Source (Host):HEK293 cellSpecies:Human
Product nameRecombinant Human CXCL10 Protein, Fc/His-tagged
+Inquiry
Cat.#:CXCL10-08HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-X-C Motif) Ligand 10
+Inquiry
Cat.#:CXCL10-105HTag:
Source (Host):Species:Human
Product nameHuman CXCL10
+Inquiry
Cat.#:CXCL10-11716HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL10, GST-tagged
+Inquiry
Cat.#:CXCL10-187HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL10 protein
+Inquiry
Cat.#:CXCL10-211HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-X-C Motif) Ligand 10, MIgG2a Fc-tagged
+Inquiry
Cat.#:CXCL10-212HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-X-C Motif) Ligand 10, HIgG1 Fc-tagged, mutant
+Inquiry
Cat.#:CXCL10-242HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-X-C Motif) Ligand 10, HIgG1 Fc-tagged
+Inquiry
Cat.#:CXCL10-274HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human CXCL10, StrepII-tagged
+Inquiry
Cat.#:CXCL10-28451THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL10
+Inquiry
Cat.#:CXCL10-29553THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL10, His-tagged
+Inquiry
Cat.#:CXCL10-31HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CXCL10, His-tagged
+Inquiry
Cat.#:CXCL10-32HTag:HIS
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-X-C Motif) Ligand 10, His-tagged
+Inquiry
Cat.#:CXCL10-524HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL10 Protein, His-tagged
+Inquiry
Cat.#:CXCL10-70HTag:
Source (Host):YeastSpecies:Human
Product nameRecombinant Human CXCL10 (IP-10)
+Inquiry
Cat.#:CXCL10-7300HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL10, None tagged
+Inquiry
Cat.#:Cxcl10-39MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-X-C Motif) Ligand 10
+Inquiry
Cat.#:Cxcl10-525MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cxcl10 Protein, His-tagged
+Inquiry
Cat.#:Cxcl10-613MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cxcl10
+Inquiry
Cat.#:CXCL10-71MTag:
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse CXCL10 (IP-10)
+Inquiry
Cat.#:Cxcl10-121RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Chemokine (C-X-C motif) Ligand 10
+Inquiry
Cat.#:CXCL10-1687RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CXCL10 Protein
+Inquiry
Cat.#:Cxcl10-526RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cxcl10 Protein, His-tagged
+Inquiry
Cat.#:Cxcl10-631RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cxcl10
+Inquiry
Cat.#:CXCL10-86RTag:
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat CXCL10
+Inquiry
Cat.#:CXCL10-1105RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CXCL10 Protein, His-tagged
+Inquiry
Cat.#:CXCL10-523DTag:His
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog CXCL10 Protein, His-tagged
+Inquiry
Cat.#:CXCL10-65CTag:
Source (Host):YeastSpecies:Canine
Product nameRecombinant Canine CXCL10 (IP-10)
+Inquiry
Cat.#:CXCL10-133BTag:N/A
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine Chemokine (C-X-C motif) Ligand 10
+Inquiry
Cat.#:CXCL10-142ETag:N/A
Source (Host):YeastSpecies:Equine
Product nameRecombinant Equine Chemokine (C-X-C motif) Ligand 10
+Inquiry
Cat.#:CXCL10-148STag:N/A
Source (Host):YeastSpecies:Pig
Product nameRecombinant Swine Chemokine (C-X-C motif) Ligand 10
+Inquiry
Cat.#:Cxcl10-388CTag:Met
Source (Host):E. coliSpecies:Cotton Rat
Product nameRecombinant Cotton Rat Cxcl10, Met-tagged
+Inquiry
Cat.#:CXCL10-50OTag:
Source (Host):YeastSpecies:Ovine
Product nameRecombinant Ovine CXCL10 (IP-10)
+Inquiry
Cat.#:CXCL10-522CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle CXCL10 Protein, His-tagged
+Inquiry
Cat.#:CXCL10-69FTag:
Source (Host):YeastSpecies:Feline
Product nameRecombinant Feline CXCL10 (IP-10)
+Inquiry
Cat.#:CXCL10-7172HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CXCL10 293 Cell Lysate
+Inquiry
Cat.#:CXCL10-9HTag:
Source (Host):Species:Human
Product nameHuman CXCL10 Reference Standard
+Inquiry

Involved Pathway

Cxcl10 involved in several pathways and played different roles in them. We selected most pathways Cxcl10 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cxcl10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
INHBC; IL13; Ccl21a; LTBR; TNFSF14; TNFSF15; GDF5; EPOR; BMPR1BB; TNFRSF1B
Chemokine signaling pathway
JAK3; CXCL3; GNGT2; CCR1; FGR; RLN1; VAV1; SHC1; PTK2; CCR8
Toll-like receptor signaling pathway
MAPK3; MAP2K4A; IFNB; CD14; IL1B; TRAF3; LY96; LBP; IFNA7; IL12B
RIG-I-like receptor signaling pathway
IFNA12; TRAF6; MAPK9; AZI2; IFNE; TBK1; FADD; ATG5; IFNB; IFNA21
Cytosolic DNA-sensing pathway
POLR2EB; CASP1; POLR3GL; IFNA7; POLR2E; TMEM173; LOC100033925; IL33; POLR3E; POLR3GLB
TNF signaling pathway
CREB3L1; MAPK1; MAP2K7; MAP2K4; CXCL10; RPS6KA4; MAPK9; MAPK11; CXCL1; MAPK12
Influenza A
MAP2K2; MAPK3; VDAC1; IFIH1; HLA-DRA; IFNA2; PRKCA; NXF1; IFNGR1; SLC25A6

Protein Function

Cxcl10 has several biochemical functions, for example, CXCR3 chemokine receptor binding, cAMP-dependent protein kinase regulator activity, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cxcl10 itself. We selected most functions Cxcl10 had, and list some proteins which have the same functions with Cxcl10. You can find most of the proteins on our site.
Function
Related Protein
Function CXCR3 chemokine receptor binding
Related Protein CXCL10; PF4; CXCL9; CXCL11.8; CXCL13; CXCL11
Function cAMP-dependent protein kinase regulator activity
Related Protein PRKAR1AB; PRKAR2AB; PRKAR1AA; PRKAG2; PRKAR1B; PRKAR2B; PRKAR2AA; PRKAR1A; PRKAR2A; CXCL10
Function chemokine activity
Related Protein CCL24; PF4; CCL34A.3; CXCL20; CXCL14; CCL38A.4; Cxcl15; XCL1; CCL20; AMCF-II
Function heparin binding
Related Protein MMP7; CTGFA; LPA; TGFBR3; PRELP; SERPINA10; AZU1; PGF; CECR1; CCL2
Function protein binding
Related Protein SPAST; MSRB3; SUPV3L1; EPO; DMBT1; RAB21; MXD4; FANCG; CNOT7; TUBA1A
Function receptor binding
Related Protein VTCN1; RCHY1; FGF10A; CXCL10; LIF; WNT11R; NRG2A; LEPROT; GCG; PTK2AB

Interacting Protein

Cxcl10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cxcl10 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cxcl10.
DPP4; DPP8

Cxcl10 Related Articles

Ma, T; Xu, JC; et al. Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model. EXPERIMENTAL AND THERAPEUTIC MEDICINE 9:1006-1012(2015).
Asquith, DL; Bryce, SA; et al. Targeting cell migration in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY 27:204-211(2015).

Cxcl10 Related Gene Family

Chemokines Cytokines