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DACT2

  • Official Full Name

    dapper homolog 2, antagonist of beta-catenin (xenopus)

  • Overview

    Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors.
  • Synonyms

    DACT2; dapper homolog 2, antagonist of beta-catenin (xenopus); Dpr2; Frd2; dapper2; A630024E20; 2900084M21Rik; dapper homolog 2; mDpr2; dapper antagonist of catenin 2; dapper, antagonist of beta-catenin, homolog 2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DACT2-2323H Recombinant Human DACT2 Protein, GST-tagged Wheat Germ GST
Human DACT2-2313HF Recombinant Full Length Human DACT2 Protein, GST-tagged In Vitro Cell Free System GST 280 amino acids
Mouse DACT2-4292M Recombinant Mouse DACT2 Protein Mammalian Cell His
Mouse DACT2-2193M Recombinant Mouse DACT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DACT2-2193M-B Recombinant Mouse DACT2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DACT2-4867Z Recombinant Zebrafish DACT2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DACT2 Related Articles

DACT2 involved in several pathways and played different roles in them. We selected most pathways DACT2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DACT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DACT2 has several biochemical functions, for example, beta-catenin binding, delta-catenin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DACT2 itself. We selected most functions DACT2 had, and list some proteins which have the same functions with DACT2. You can find most of the proteins on our site.

Function Related Protein
beta-catenin bindingBCL9;SOX17;PTPRK;BTRC;CD2AP;GLI3;SOX9;APC;HDAC6
delta-catenin bindingDACT2;DACT3;CDH24;DACT1;PTPRJ;PLEKHA7;PLEKHA7A
protein bindingLIN28B;VENTX;PLAUR;PIKFYVE;ID4;WRAP53;Cd24a;TCTN2;ASIC2
protein kinase A bindingNBEA;RARA;AKAP13;AKAP6;DACT2;AKAP17A;AKAP5;Akap2;DACT3
protein kinase C bindingHDAC7A;HSPB1;PARD6A;PKN1;SDC4;ADAM9;TWF2;C1QBP;YWHAG
transcription factor bindingNCOA2;TWIST1;HHEX;HDAC3;CAMTA2;CD34;ATOH8;AIP;CTBP1

DACT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DACT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DACT2.

Hdac1; Ctnnd2; Vang; dco; Tcf3; Lef1; Ctnnd1; GSK3A; dsh; Dvl1; Prkcg; Csnk2b; Tcf7; Ctnnb1; Dact3; Tcf4; Dvl2; Dvl3; Tgfbr1

Schussel, JL; Kalinke, LP; et al. Expression and epigenetic regulation of DACT1 and DACT2 in oral squamous cell carcinoma. CANCER BIOMARKERS 15:11-17(2015).
Zhao, ZY; Herman, JG; et al. Methylation of DACT2 Promotes Papillary Thyroid Cancer Metastasis by Activating Wnt Signaling. PLOS ONE 9:-(2014).
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