dapk3
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  • Official Full Name
  • death-associated protein kinase 3
  • Background
  • Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells.These results suggest that DAPK3 may play a role in the induction of apoptosis.
  • Synonyms
  • DAPK3; death-associated protein kinase 3; ZIP; ZIPK; dlk; ZIP-kinase; DAP kinase 3; MYPT1 kinase; DAP-like kinase; ZIP kinase isoform; zipper-interacting protein kinase; FLJ36473
Cat.#:DAPK3-2340HTag:GST
Source (Host):Insect CellsSpecies:Human
Product nameRecombinant Human DAPK3 Protein, GST-tagged
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Cat.#:DAPK3-2341HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DAPK3 Protein, GST-tagged
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Cat.#:DAPK3-984HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human DAPK3 Protein, MYC/DDK-tagged
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Cat.#:DAPK3-291HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DAPK3, GST-tagged, Active
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Cat.#:DAPK3-292HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DAPK3, 1-659, GST-tagged, Active
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Cat.#:DAPK3-30752THTag:
Source (Host):Species:Human
Product nameRecombinant Human DAPK3
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Cat.#:Dapk3-1405MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Dapk3 protein, His & T7-tagged
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Cat.#:DAPK3-4306MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DAPK3 Protein
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Cat.#:DAPK3-1775RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DAPK3 Protein
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Cat.#:DAPK3-1177RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DAPK3 Protein, His-tagged
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Cat.#:DAPK3-892HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Death-Associated Protein Kinase 3, GST-tagged
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Cat.#:DAPK3-616HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human DAPK3 cell lysate
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Involved Pathway

DAPK3 involved in several pathways and played different roles in them. We selected most pathways DAPK3 participated on our site, such as Apoptosis, Bladder cancer, Caspase activation via extrinsic apoptotic signalig pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAPK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Apoptosis
BIRC5A; IL1B2; BOK; STK24B; TNF; E2F1; DBNLB; CDK5RAP2; CASP3B; RELA
Bladder cancer
THBS1; VEGFA; RAF1; KRAS; DAPK2; E2F1; HBEGF; RPS6KA5; IL-8; ARAF
Caspase activation via extrinsic apoptotic signalig pathway
CASP8L1; TICAM1; DCC; DAPK3; DAPK1; RNF8
Ligand-independent caspase activation via DCC
DAPK3; DAPK1; RNF8
Pathways in cancer
BDKRB1; NFKB1; HSP90AA1; GNG13; WNT5A; ETS1; PTCH1; CBLB; GNAS; STAT1
Programmed Cell Death
DSP; DBNLA; STK26; BMX; MLKL; DSG1; DBNL; GZME; GAS2; GZMF

Protein Function

DAPK3 has several biochemical functions, for example, ATP binding, Rho GTPase binding, cAMP response element binding protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAPK3 itself. We selected most functions DAPK3 had, and list some proteins which have the same functions with DAPK3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PRKCQ; DDX53; PDK1; UBE2D1A; PTK2AB; NAGK; NTRK3; ABCG2C; ACSM3; MYO5C
Function Rho GTPase binding
Related Protein INF2; DAAM1B; DOCK9; DIAP3; DIAPH1; ANTXR2A; ARHGEF2; PFN1; ROCK2B; LRRK2
Function cAMP response element binding protein binding
Related Protein CREM; KCNA3; ATF2; CRTC1A; CRTC1; CREB3; CRTC3; CRTC2; DDIT3; DAPK3
Function identical protein binding
Related Protein THG1L; SMAD3; GPSM2; AGXT2; ETNPPL; FHOD1; SAFB2; IFIT3; TP63; GCC2
Function leucine zipper domain binding
Related Protein MKL1; DDIT3; ERC1; ATF4; DAPK3; PAWR; PMF1; AATF; NRL; CRX
Function protein binding
Related Protein RMI1; IL1RN; SMARCD1; ACLY; RAB11FIP3; MID2; PDIK1L; MAGEE1; C12orf50; SLC6A20B
Function protein homodimerization activity
Related Protein MBL1; DRD2; CCBL2; BMP7A; KLRB1B; PDK2; BMPR1A; S100A11; HOGA1; SFTPC
Function protein serine/threonine kinase activity
Related Protein TESK1; SNRKA; ILK; STK32A; DCLK3; PRKCZ; ROCK2A; PRKAA2; NEK5; RPS6KB1B

Interacting Protein

DAPK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAPK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAPK3.
TCP10L; PPP1R12A; MYL12B; Daxx; HSP90AB1; ATF4; STAT3; Rhod; CDC37

DAPK3 Related Articles

Marina, O; Hainz, U; et al. Serologic Markers of Effective Tumor Immunity against Chronic Lymphocytic Leukemia Include Nonmutated B-Cell Antigens. CANCER RESEARCH 70:1344-1355(2010).