DECR1
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Official Full Name
2,4-dienoyl CoA reductase 1, mitochondrial
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Overview
This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. -
Synonyms
DECR1; 2,4-dienoyl CoA reductase 1, mitochondrial; DECR; 2,4-dienoyl-CoA reductase, mitochondrial; SDR18C1; short chain dehydrogenase/reductase family 18C; member 1; 4-enoyl-CoA reductase; short chain dehydrogenase/reductase family 18C, member 1; NADPH;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cynomolgus Monkey
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- DECR1 Related Articles
DECR1 involved in several pathways and played different roles in them. We selected most pathways DECR1 participated on our site, such as Fatty Acid Beta Oxidation, Fatty Acid Biosynthesis, Fatty acid, triacylglycerol, and ketone body metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DECR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Fatty Acid Beta Oxidation | ECI1;CPT1B;SLC25A20;CHKB;DECR1;CPT1A;CPT2;CRAT |
Fatty Acid Biosynthesis | ACSL4;ACSL4B;ACACB;ACSL5;OXSM;ACACA;ACSL1B;ECH1;ACSL1 |
Fatty acid, triacylglycerol, and ketone body metabolism | MED7;DGAT1B;ACOT11B;MED20;CPT2;MTF1;MED22;ACOT11A;MED19 |
Metabolism | GPHN;SLC4A1B;CYP8B2;GLTPD1;COX6A1;SLC25A32;DAO1;NAGS;UGT1B7 |
Metabolism of lipids and lipoproteins | NEU4;VAPB;MED9;CYP2AD3;CEPT1A;FAAH2;CDK19;PLD6;PEMT |
Mitochondrial Fatty Acid Beta-Oxidation | ECI1;ACAD11;DECR1 |
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids |
DECR1 has several biochemical functions, for example, 2,4-dienoyl-CoA reductase (NADPH) activity, NADPH binding, oxidoreductase activity, acting on NAD(P)H. Some of the functions are cooperated with other proteins, some of the functions could acted by DECR1 itself. We selected most functions DECR1 had, and list some proteins which have the same functions with DECR1. You can find most of the proteins on our site.
Function | Related Protein |
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2,4-dienoyl-CoA reductase (NADPH) activity | DECR1;DECR2 |
NADPH binding | CBR4;QDPR;FASN;CBR3;DECR1;CRYZ;GRHPR;DHFR;HMGCR |
oxidoreductase activity, acting on NAD(P)H | NDUFS8B;DERL3;ECSIT;DECR1;NDUFS8A;MIOX;WDR93;AIFM1 |
DECR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DECR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DECR1.
PTTG1; thiI; ssrna_au; Ktn1; NOP56; CCDC22; AK1; ESR1; NPM1; VCAM1; NSS; RPL10; JAK3; MSH6
- Q&As
- Reviews
Q&As (7)
Ask a questionDECR1 works alongside other enzymes in β-oxidation, ensuring effective fatty acid degradation.
DECR1 plays a role in energy production by aiding in the efficient processing of fatty acids in mitochondria.
Mutations in DECR1 can impact fatty acid metabolism, potentially leading to metabolic disorders.
It specifically catalyzes the reduction of double bonds in unsaturated fatty acids, facilitating their breakdown.
Altered DECR1 activity can affect energy balance and fat metabolism, influencing conditions like diabetes and obesity.
Targeting DECR1 could offer new treatment avenues for managing metabolic conditions like obesity and diabetes.
DECR1, or 2,4-dienoyl-CoA reductase 1, is key in the metabolism of unsaturated fatty acids, particularly in β-oxidation.
Customer Reviews (3)
Write a reviewInvaluable support. Crucial for protein experiments.
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Swift and accurate. An asset to our research.
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