AMIGO2
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Official Full Name
adhesion molecule with Ig like domain 2
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Synonyms
AMIGO2; adhesion molecule with Ig like domain 2; amphoterin-induced protein 2; ALI 1; ALI1; Alivin 1; Alivin1; AMIGO 2; Amphoterin Induced Gene 2; Amphoterin induced protein 2; DEGA; Differentially expressed in gastric adenocarcinoma; Differentially expressed in gastric adenocarcinomas; Transmembrane protein AMIGO 2; Transmembrane protein AMIGO2; AMIGO-2; alivin-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rat
- E.coli
- HEK293
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- AMIGO2 Related Articles
AMIGO2 involved in several pathways and played different roles in them. We selected most pathways AMIGO2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMIGO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
AMIGO2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMIGO2 itself. We selected most functions AMIGO2 had, and list some proteins which have the same functions with AMIGO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SVIL;BCL2L16;QRICH1;NPL;BMPR2;DDIT4L;ZFP143;PHF7;HEY1 |
AMIGO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMIGO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AMIGO2.
CACNA1A
- Q&As
- Reviews
Q&As (10)
Ask a questionAltered expression or dysregulation of AMIGO2 has been associated with neurological disorders, including autism spectrum disorders and epilepsy, highlighting its potential role in disease pathogenesis.
AMIGO2 exhibits a dynamic expression pattern in the developing and adult brain, with high expression in regions involved in neuronal development, such as the cortex, hippocampus, and cerebellum.
Knockout or overexpression studies of AMIGO2 have revealed its essential role in neuronal development and function, impacting processes such as neurite outgrowth, synaptogenesis, and neuronal survival.
AMIGO2 is involved in modulating synaptic plasticity and neurotransmission, regulating the activity and surface expression of neurotransmitter receptors and contributing to the refinement of synaptic connectivity.
AMIGO2 influences dendritic arborization and synaptic connectivity, promoting dendritic branching and the formation of mature dendritic spines, which are crucial for synaptic transmission and plasticity.
AMIGO2 plays a role in myelination and oligodendrocyte development, contributing to proper myelin sheath formation and the maturation of oligodendrocytes.
Modulation of AMIGO2 expression or activity holds potential as a therapeutic approach for neurological conditions, and further investigation into its specific mechanisms and interactions may unveil novel strategies for intervention and treatment.
AMIGO2 is involved in axon guidance and pathfinding, guiding axons to their appropriate targets during neuronal development, and contributing to the establishment of neuronal circuitry.
AMIGO2 plays a critical role in neuronal migration during brain development, regulating the proper positioning and layering of neurons in the developing cerebral cortex.
AMIGO2 interacts with various cell adhesion molecules and signaling proteins, including members of the immunoglobulin superfamily and growth factor receptors, activating downstream signaling pathways involved in cell adhesion, cytoskeletal remodeling, and synaptic plasticity.
Customer Reviews (3)
Write a reviewVersatility in multiple assay formats and platforms.
Excellent reproducibility in protein expression profiling.
Stable reagents for long-term storage and repeated use.
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