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DHDDS

  • Official Full Name

    dehydrodolichyl diphosphate synthase

  • Overview

    The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  • Synonyms

    DHDDS; dehydrodolichyl diphosphate synthase; DS; FLJ13102; HDS; Dedol PP synthase; dedol-PP synthase; cis-prenyl transferase; cis-isoprenyltransferase; CIT; CPT; RP59;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DHDDS-2583H Recombinant Human DHDDS Protein, GST-tagged Wheat Germ GST
Human DHDDS-6948HCL Recombinant Human DHDDS 293 Cell Lysate HEK293 N/A
Human DHDDS-2524HF Recombinant Full Length Human DHDDS Protein, GST-tagged In Vitro Cell Free System GST 294 amino acids
Human DHDDS-2138H Recombinant Human DHDDS Protein (1-333 aa), GST-tagged E.coli GST 1-333 aa
Mouse Dhdds-2543M Recombinant Mouse Dhdds Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish DHDDS-12399Z Recombinant Zebrafish DHDDS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DHDDS involved in several pathways and played different roles in them. We selected most pathways DHDDS participated on our site, such as Terpenoid backbone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHDDS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Terpenoid backbone biosynthesisMVD;ACAT1;PDSS1;NUS1;IDI1;ACAT2;IDI2;ZMPSTE24;HMGCS2

DHDDS has several biochemical functions, for example, contributes_to polyprenyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DHDDS itself. We selected most functions DHDDS had, and list some proteins which have the same functions with DHDDS. You can find most of the proteins on our site.

Function Related Protein
contributes_to polyprenyltransferase activity
protein bindingPLUNC;BATF2;PLD1;PTPRB;ARR3;TPP1;TBXA2R;C22orf29;TCL1A

DHDDS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHDDS here. Most of them are supplied by our site. Hope this information will be useful for your research of DHDDS.

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