dhx15
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  • Official Full Name
  • DEAH (Asp-Glu-Ala-His) box polypeptide 15
  • Background
  • The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing.
  • Synonyms
  • DHX15; DEAH (Asp-Glu-Ala-His) box polypeptide 15; DDX15, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 15; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; DBP1; HRH2; PRP43; PRPF43; PrPp43p; ATP dependent RNA helicase #46; DDX15; DEADH box 15; DEAH (Asp Glu Ala His) box polypeptide 15; DEAH box polypeptide 15; DEAH box protein 15; RNA helicase 2; DEAD/H box-15; OTTHUMP00000217985; ATP-dependent RNA helicase #46; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15
Cat.#:DHX15-05HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human DHX15 Protein, His-tagged
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Cat.#:DHX15-2300HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human DHX15 Protein, MYC/DDK-tagged
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Cat.#:DHX15-2606HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DHX15 Protein, GST-tagged
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Cat.#:DHX15-1261RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DHX15 Protein, His-tagged
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Cat.#:DHX15-2829CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DHX15
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Cat.#:DHX15-6551ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DHX15
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Cat.#:DHX15-6933HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DHX15 293 Cell Lysate
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Involved Pathway

DHX15 involved in several pathways and played different roles in them. We selected most pathways DHX15 participated on our site, such as Spliceosome, mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Spliceosome
SRSF9; PLRG1; U2AF1; U2AF2A; DHX16; U2SURP; SNRPD1; PRPF19; SF3A2; SRSF5A
mRNA processing
SF3B2; HNRNPH2; DDX39; HNRNPH1L; CLK4; RBM5; EBI3; ZFP346; ZFP740; CLASRP

Protein Function

DHX15 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX15 itself. We selected most functions DHX15 had, and list some proteins which have the same functions with DHX15. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein DGKB; HELZ2; NTRK1; ABL2; ACLYA; RPS6KA4; ROS1; ATP2B3A; ACSM5; BCR
Function ATP-dependent RNA helicase activity
Related Protein EIF4A1; DHX29; DHX35; DDX3X; DHX38; DDX59; DHX8; DDX19; DDX46; DDX27
Function RNA helicase activity
Related Protein PRIM2; CTU1; UAP1L1; SKIV2L2; DDX6; FAM120B; DHX15; DDX5; DDX17; RAD54B
Function double-stranded RNA binding
Related Protein DHX30; MBNL1; DHX15; STAU1; ELAVL1; DROSHA; EIF2AK2; APTX; TUBB4B; OAS3
Function poly(A) RNA binding
Related Protein RPL21; UBE2I; ALDH18A1; SRSF9; SNIP1; RARS2; ETF1A; GAR1; MRPS23; XRN2
Function protein binding
Related Protein HDAC2; HSPH1; CXCL9; PSMC5; KCNJ6; CYC1; PPIG; GADD45B; IGFBP5; SSTR3

Interacting Protein

DHX15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX15 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX15.
RBM5; RBM17

DHX15 Related Articles

Pattabhi, S; Gale, M; et al. DHX15: A novel regulator of innate immune defense to RNA virus infections. CYTOKINE 70:63-63(2014).
Lu, HB; Lu, N; et al. DHX15 Senses Double-Stranded RNA in Myeloid Dendritic Cells. JOURNAL OF IMMUNOLOGY 193:1364-1372(2014).