dock10
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  • Official Full Name
  • dedicator of cytokinesis 10
  • Background
  • Dock10 (Dedicator of cytokinesis), also known as Zizimin3, is a large (~240 kDa) protein involved in intracellular signalling networks.It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors which function as activators of small G proteins.
  • Synonyms
  • DOCK10; dedicator of cytokinesis 10; dedicator of cytokinesis protein 10; KIAA0694; ZIZ3; zizimin3; zizimin-3; protein zizimin 3; dopamine receptor interacting protein 2; DRIP2; Nbla10300; DKFZp781A1532
Cat.#:DOCK10-2804HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DOCK10 Protein, GST-tagged
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Cat.#:DOCK10-12117HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DOCK10, His-tagged
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Involved Pathway

DOCK10 involved in several pathways and played different roles in them. We selected most pathways DOCK10 participated on our site, such as Factors involved in megakaryocyte development and platelet production, Hemostasis, Regulation of CDC42 activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with DOCK10 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Factors involved in megakaryocyte development and platelet production
KIF26A; KIF4; DOCK8; AKAP1B; IRF2A; HBBE1.1; ITPK1; BA1; KIF3B; IRF1B
Hemostasis
LOC100514666; CD177; MERTK; CABLES1; MMRN2A; GATA2A; MAFF; MAFG; CAP1; SIRPA
Regulation of CDC42 activity
DNMBP; DOCK9; ARHGAP17; ARHGAP1; SPATA13; DOCK6; DOCK10; MCF2L; ARHGEF25; ITSN2

Protein Function

DOCK10 has several biochemical functions, for example, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by DOCK10 itself. We selected most functions DOCK10 had, and list some proteins which have the same functions with DOCK10. You can find most of the proteins on our site.
Function
Related Protein
Function Rho GTPase binding
Related Protein ANTXR2A; CDC42BPB; DOCK11; DAPK3; AKAP13; FMNL2; DIAPH1; DAAM1B; DIAP1; IQGAP3
Function Rho guanyl-nucleotide exchange factor activity
Related Protein FGD; FGD2; ARHGEF19; FARP2; ARHGEF11; ARHGEF28; TIAM2; ARHGEF1; FGD4A; ARHGEF40
Function molecular_function
Related Protein ARL6IP5A; SOWAHCB; FAM65C; RCCD1; ZNF75A; CCDC81; EMC10; DEFA25; DEFA24; SSX2IPA
Function protein binding
Related Protein C21orf2; PRSS8; KCTD6; SELPLG; SH3GLB1; RTP3; IKBKG; RB1; RTP4; NPAS2

Interacting Protein

DOCK10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOCK10 here. Most of them are supplied by our site. Hope this information will be useful for your research of DOCK10.
LURAP1