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DOCK5

Official Full Name

dedicator of cytokinesis 5
Overview

Dock5 (Dedicator of cytokinesis 5), also known as DOCK5, is a large (~180 kDa) protein involved in intracellular signalling networks.It is a member of the DOCK-A subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins.Dock5 is predicted to activate the small G protein Rac.
Synonyms

DOCK5; dedicator of cytokinesis 5; dedicator of cytokinesis protein 5; FLJ21034; DKFZp451J181; DKFZp779M164; DKFZp781J211;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	DOCK5-2807H	Recombinant Human DOCK5 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	DOCK5-1367H	Recombinant Human DOCK5 Protein, His-tagged	E.coli	N-His	Ala1749-Gln1870	Inquiry
Human	DOCK5-2224H	Recombinant Human DOCK5 Protein (Arg425-Cys609), N-His tagged	E.coli	N-His	Arg425-Cys609	Inquiry
Mouse	DOCK5-4755M	Recombinant Mouse DOCK5 Protein	Mammalian Cell	His		Inquiry
Mouse	DOCK5-2480M-B	Recombinant Mouse DOCK5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	DOCK5-2480M	Recombinant Mouse DOCK5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Dock5-1368M	Recombinant Mouse Dock5 Protein, His-tagged	E.coli	N-His	Met1-Leu284	Inquiry
Zebrafish	DOCK5-6086Z	Recombinant Zebrafish DOCK5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

DOCK5 involved in several pathways and played different roles in them. We selected most pathways DOCK5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DOCK5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

DOCK5 has several biochemical functions, for example, guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DOCK5 itself. We selected most functions DOCK5 had, and list some proteins which have the same functions with DOCK5. You can find most of the proteins on our site.

Function	Related Protein
guanyl-nucleotide exchange factor activity	RAPGEF1B;SERGEF;VAV3;GCGR;RASGRF2B;FNIP1;TBC1D10A;RIC8B;CHRM4

DOCK5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOCK5 here. Most of them are supplied by our site. Hope this information will be useful for your research of DOCK5.