dtymk
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  • Official Full Name
  • deoxythymidylate kinase (thymidylate kinase)
  • Background
  • Thymidylate kinase also known as deoxythymidylate kinase or dTMP kinase is an enzyme that in humans is encoded by the DTYMK gene. and belongs to thymidylate kinase family of proteins.
  • Synonyms
  • DTYMK; deoxythymidylate kinase (thymidylate kinase); thymidylate kinase; CDC8; dTMP kinase; thymidylate (dTMP) kinase; TMPK; TYMK; PP3731; FLJ44192; MGC198617
Cat.#:DTYMK-2911HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DTYMK Protein, GST-tagged
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Cat.#:DTYMK-3562HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DTYMK, His-tagged
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Cat.#:DTYMK-12195HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DTYMK, His-tagged
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Cat.#:DTYMK-28069THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DTYMK, His-tagged
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Cat.#:DTYMK-4861MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DTYMK Protein
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Cat.#:Dtymk-8232MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Dtymk protein, His & T7-tagged
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Cat.#:Dtymk-8233RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Dtymk protein, His & T7-tagged
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Cat.#:DTYMK-1344RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DTYMK Protein, His-tagged
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Cat.#:DTYMK-5406CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DTYMK
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Cat.#:DTYMK-3479ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DTYMK
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Cat.#:DTYMK-6791HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DTYMK 293 Cell Lysate
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Involved Pathway

DTYMK involved in several pathways and played different roles in them. We selected most pathways DTYMK participated on our site, such as Metabolic pathways, Metabolism, Metabolism of nucleotides, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTYMK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolic pathways
DAO.2; SPTLC1; NDUFA5; SPRA; PIP5KL1; AKR1B1L; DNMT3B; RDH10A; PDHA1B; MAOA
Metabolism
ARSI; SLC35D2; CPNE7; CYB5R3; CYP2AD6; MED26; NHLRC1; PDP1; CYP19A1; UGT1B4
Metabolism of nucleotides
ADA; AK7; ITPA; NUDT5; DPYD; ADSS; PROZA; ADAL; DGUOK; ADK
Pyrimidine metabolism
ENTPD8; POLR2K; RRM2B; NT5E; NME7; CTPS1A; CMPK; POLR3A; DPYS; POLR2EB
Synthesis and interconversion of nucleotide di- and triphosphates
DTYMK; AK8; GLRX; GRX2; AK7; AK7A
pyrimidine deoxyribonucleotide phosphorylation
DTYMK; CMPK2
pyrimidine deoxyribonucleotides biosynthesis from CTP
DTYMK
pyrimidine deoxyribonucleotides de novo biosynthesis
DUT; DTYMK

Protein Function

DTYMK has several biochemical functions, for example, ATP binding, nucleoside phosphate kinase activity, thymidylate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DTYMK itself. We selected most functions DTYMK had, and list some proteins which have the same functions with DTYMK. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PDK1; PSMC3; HSPA5; SLFN5; LIG1; PANK1B; MYO6B; ATP4A; KATNA1; SPAST
Function nucleoside phosphate kinase activity
Related Protein AK9; DTYMK
Function thymidylate kinase activity
Related Protein CMPK2; DTYMK
Function uridylate kinase activity
Related Protein CMPK; DTYMK; CMPK1

Interacting Protein

DTYMK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTYMK here. Most of them are supplied by our site. Hope this information will be useful for your research of DTYMK.
HSD17B7; CDC5L

DTYMK Related Articles

Liu, Y; Marks, K; et al. Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer. CANCER DISCOVERY 3:870-879(2013).
Felizardo, TC; Foley, J; et al. Harnessing autophagy for cell fate control gene therapy. AUTOPHAGY 9:1069-1079(2013).