Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

DVL3

Official Full Name

dishevelled segment polarity protein 3
Overview

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]
Synonyms

DVL3; dishevelled segment polarity protein 3; segment polarity protein dishevelled homolog DVL-3; DSH homolog 3; dishevelled-3; dishevelled, dsh homolog 3; dishevelled 3 (homologous to Drosophila dsh);

Type

Recombinant Proteins
Cell & Tissue Lysates
Antibody
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|GST
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	DVL3-28353TH	Recombinant Human DVL3	Wheat Germ	N/A	716 amino acids	Inquiry
Human	DVL3-2961H	Recombinant Human DVL3 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	DVL3-28354TH	Recombinant Human DVL3	Wheat Germ	N/A	100 amino acids	Inquiry
Human	DVL3-6764HCL	Recombinant Human DVL3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	DVL3-1843H	Recombinant Human DVL3 protein, His & GST-tagged	E.coli	His/GST	His545~Met716 (Accession # Q92997)	Inquiry
Human	CPBT-Y0051RH	Goat Anti-Human DVL3 Polyclonal Antibody		N/A		Inquiry
Human	DVL3-4137HF	Recombinant Full Length Human DVL3 Protein, GST-tagged	In Vitro Cell Free System	GST	716 amino acids	Inquiry
Human	DVL3-142HF	Recombinant Full Length Human DVL3 Protein	In Vitro Cell Free System		716 amino acids	Inquiry
Human	DVL3-2014H	Recombinant Human DVL3 Protein (His545-Met716), N-GST tagged	E.coli	N-GST	His545-Met716	Inquiry
Mouse	DVL3-4901M	Recombinant Mouse DVL3 Protein	Mammalian Cell	His		Inquiry
Mouse	DVL3-2576M	Recombinant Mouse DVL3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	DVL3-2576M-B	Recombinant Mouse DVL3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
DVL3 Related Signal Pathway

DVL3 involved in several pathways and played different roles in them. We selected most pathways DVL3 participated on our site, such as Basal cell carcinoma, Beta-catenin independent WNT signaling, Canonical Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DVL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Basal cell carcinoma	SETD6;DVL1;WNT5B;FZD6;SMO;TP53;WNT6;WNT7B;WNT1
Beta-catenin independent WNT signaling	AP2A1;CLTC;PRICKLE1;DVL2;AP2M1;DVL3;MOV10;PRICKLE1B;ITPR2
Canonical Wnt signaling pathway	CSNK1D;CSNK1E;KLHL12;DVL3;DVL2;CSNK1A1;DVL1
DNA damage response (only ATM dependent)	MLKL;BIK;DVL3;DVL1;DVL2
Degradation of DVL	HECW1B;HECW1;DVL3;DACT1;DVL1;KLHL12;DVL2
Disassembly of the destruction complex and recruitment of AXIN to the membrane	WNT8-2;DVL3;DVL2;CSNK1G2;DVL1
HTLV-I infection	STAT5A;SFPI1;CCND3;CCND1;SLC2A1;CD3D;VDAC2;NFATC3;ELK1
Hippo signaling pathway	CRB2;PPP1CC;TCF7L2;ITGB2;TCF7;PARD6B;FZD9;SMAD1;CTNNA2

DVL3 has several biochemical functions, for example, beta-catenin binding, frizzled binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DVL3 itself. We selected most functions DVL3 had, and list some proteins which have the same functions with DVL3. You can find most of the proteins on our site.

Function	Related Protein
beta-catenin binding	DACT2;GRIP1;TCF7L1B;PSEN1;Ar;MED12;TCF7L2;TRPC4;HDAC6
frizzled binding	SFRP1;WNT9B;DVL3;BAMBI;WNT5A;WNT2BA;WNT1;WNT7AA;WNT9A
protease binding	Cstb;ADAM8A;ADRM1;IL1R1;KIT;SERPINC1;TIMP2;CHL1;SERPINF2
protein binding	KHK;ACVR2A;CD200R2;PAN3;THOC7;ERCC3;TAC1;CDKL3;GRB10
protein heterodimerization activity	UGT1A4;BAXA;SRI;UGT1A3;HER1;ZHX3;H3F3C;GRIN2A;HGF
receptor binding	AGRP;KNG1;LRRC4B;FGF8A;ICAM3;Fgf15;PECI;MYO1C;ANGPTL2

DVL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DVL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DVL3.

CSNK1D; DVL1; ADAP1; STOM; CSNK1E; RWDD2B