DEFB1
-
Official Full Name
defensin, beta 1
-
Overview
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. -
Synonyms
beta 1; BD 1; BD-1; BD1; Beta defensin 1; Beta-defensin 1; DEFB 1; DEFB1; DEFB1_HUMAN; DEFB101; Defensin; Defensin beta 1; Defensin beta 1 preproprotein; HBD 1; hBD-1; HBD1; MGC51822;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cattle
- Chicken
- Human
- Mouse
- Pig
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- Fc
- GST
- His
- His (Fc)
- Avi
- His|GST
- His|S
- SUMO
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
DEFB1 involved in several pathways and played different roles in them. We selected most pathways DEFB1 participated on our site, such as Beta defensins, Defensins, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with DEFB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Beta defensins | DEFB119;DEFB116;DEFB106A;DEFB4A;DEFB104A;DEFB129;DEFB103A;DEFB125;CCR6 |
Defensins | CCR6;DEFB129;DEFA6;DEFB1;DEFB104A;DEFA5;ART1;DEFB106A;DEFB103A |
Immune System | ACTR2B;LILRA3;CLEC6A;ACTR1B;DDOST;NLRC5;TXNIP;CD160;OASL |
Innate Immune System | TREM1;WASF3;PANX1B;PELI2;CLEC4D;NLRP4;RCA2.1;MB21D1;DEFA5 |
DEFB1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DEFB1 itself. We selected most functions DEFB1 had, and list some proteins which have the same functions with DEFB1. You can find most of the proteins on our site.
Function | Related Protein |
---|
DEFB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEFB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DEFB1.
RhoA; MAP4K2
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, the antimicrobial properties of DEFB1 make it a potential target for the development of novel therapeutics against various infectious diseases.
Research suggests that combining DEFB1 with conventional antibiotics may enhance the overall antimicrobial activity and reduce the risk of antibiotic resistance.
DEFB1 plays a role in maintaining the balance of the microbiome by preventing the overgrowth of harmful microorganisms. It contributes to the dynamic equilibrium in the microbial community.
Some studies suggest that DEFB1 may have a role in cancer, with evidence indicating both tumor-promoting and tumor-suppressing effects depending on the specific context.
Yes, variations in the DEFB1 gene can influence its expression levels, impacting an individual's susceptibility to certain infections and inflammatory conditions.
Customer Reviews (3)
Write a reviewthe stability of the DEFB1 protein enables me to conduct experiments over an extended period, reducing the need for frequent restocking and promoting experimental consistency.
The DEFB1 protein offers significant advantages in trials due to its high quality, purity, and stability.
the manufacturer's exceptional support greatly enhances my research process.
Ask a Question for All DEFB1 Products
Required fields are marked with *
My Review for All DEFB1 Products
Required fields are marked with *