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ECE2

  • Official Full Name

    endothelin converting enzyme 2

  • Overview

    Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally;pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 (PubMed 11718899)).
  • Synonyms

    ECE2; endothelin converting enzyme 2; endothelin-converting enzyme 2; KIAA0604; MGC2408; MGC78487; ECE 2; ECE-2; ECE2_HUMAN; Endothelin-converting enzyme 2 region; Hypothetical protein MGC2408; MGC17664;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian cells
  • Wheat Germ
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • His|Val
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ECE2-529H Active Recombinant Human ECE2, His&Val-tagged Mammalian cells His/Val
Human ECE2-12265H Recombinant Human ECE2, His-tagged E.coli His 1-255a.a.
Human ECE2-690H Recombinant Human ECE2, Fc tagged Human Cell Fc
Human ECE2-3028H Recombinant Human ECE2 Protein, GST-tagged Wheat Germ GST
Human ECE2-3813H Recombinant Human ECE2, His tagged HEK293 His Gly 199-Trp 883
Human ECE2-2052HCL Recombinant Human ECE2 cell lysate Human Cell N/A
Human ECE2-2976HCL Recombinant Human ECE2 cell lysate Human Cell N/A
Human ECE2-4351H Recombinant Human ECE2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ECE2-4152HF Recombinant Full Length Human ECE2 Protein, GST-tagged In Vitro Cell Free System GST 255 amino acids
Human ECE2-1877H Recombinant Human ECE2 protein, GST-tagged E.coli GST 1-255 aa
Human ECE2-4351H-B Recombinant Human ECE2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Ece2-222M Recombinant Mouse Ece2 Protein, His-tagged E.coli His Met1~Phe163
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ECE2 Related Articles
  • ECE2 Related Research Area

ECE2 involved in several pathways and played different roles in them. We selected most pathways ECE2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ECE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ECE2 has several biochemical functions, for example, metal ion binding, metalloendopeptidase activity, methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ECE2 itself. We selected most functions ECE2 had, and list some proteins which have the same functions with ECE2. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingPOLB;TNFRSF11A;NUPL2;NCALDA;DDX11;NUBP1;TPH1A;ZFP64;A3GALT2
metalloendopeptidase activityMMP11;ADAM32;ADAM7;ADAM1B;MEP1A.2;PAPPAB;ADAM15;ADAM21;TLL2
methyltransferase activityPRDM14;SETDB1B;SMYD5;SUV39H1A;METTL23;METTL6;METTL25;WBP7;NSUN4
protein bindingRARG;COA3;VPS8;NRBP1;OCLN;DRAXIN;YTHDF3;FBXO32;PPP2R5A

ECE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ECE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ECE2.

SYNE4; NDUFS1; CD86; CASP10

Maguire, JJ; Davenport, AP; et al. Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12. BRITISH JOURNAL OF PHARMACOLOGY 171:5555-5572(2014).
Mouthon, L; Bussone, G; et al. Scleroderma Renal Crisis. JOURNAL OF RHEUMATOLOGY 41:1040-1048(2014).
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