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EDF1

  • Official Full Name

    endothelial differentiation-related factor 1

  • Overview

    This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.
  • Synonyms

    EDF1; endothelial differentiation-related factor 1; EDF 1; multiprotein bridging factor 1; MBF1; EDF-1; MGC9058;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Myc
  • DDK
  • GST
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EDF1-12280H Recombinant Human EDF1, GST-tagged E.coli GST 1-148a.a.
Human EDF1-525H Recombinant Human EDF1 Protein, His-tagged E.coli His
Human EDF1-2774H Recombinant Human EDF1, His-tagged E.coli His
Human EDF1-28461TH Recombinant Human EDF1, His-tagged E.coli His
Human EDF1-3052H Recombinant Human EDF1 Protein, GST-tagged Wheat Germ GST
Human EDF1-6723HCL Recombinant Human EDF1 293 Cell Lysate HEK293 N/A
Human EDF1-108H Recombinant Human EDF1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human EDF1-2258H Recombinant Human EDF1 Protein (Ala2-Lys148), C-His tagged Mammalian cells C-His Ala2-Lys148
Human EDF1-2704H Recombinant Human EDF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EDF1-4188HF Recombinant Full Length Human EDF1 Protein, GST-tagged In Vitro Cell Free System GST 148 amino acids
Mouse Edf1-2727M Recombinant Mouse Edf1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque EDF1-1379R Recombinant Rhesus monkey EDF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EDF1-1204R Recombinant Rhesus Macaque EDF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EDF1-1204R-B Recombinant Rhesus Macaque EDF1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EDF1-11008Z Recombinant Zebrafish EDF1 Mammalian Cell His
Chicken EDF1-1352C Recombinant Chicken EDF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

EDF1 involved in several pathways and played different roles in them. We selected most pathways EDF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EDF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

EDF1 has several biochemical functions, for example, calmodulin binding, NOT histone acetyltransferase activity, NOT methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EDF1 itself. We selected most functions EDF1 had, and list some proteins which have the same functions with EDF1. You can find most of the proteins on our site.

Function Related Protein
calmodulin bindingEEA1;PPP3CC;MAP6;TTN;CNN1;MTAP6;TRPV6;SPTBN1;CAMK1D
NOT histone acetyltransferase activityEDF1;ARRB1;BRCA2;BAZ1A
NOT methyltransferase activity
poly(A) RNA bindingSFRS9;PPP1R10;TPT1;XRCC5;PATL1;SNRPD3;C3orf26;ADAR;FXR2
protein bindingBNIPL;RNF149;PAX9;HEY2;NLRP2;PSG1;NCALD;FAM50B;DEPDC1
sequence-specific DNA bindingRXRBA;DRGX;FOXC2;THRAA;ZNF215;CTCF;SOX21B;GRHL2A;HMX3
transcription coactivator activityTFDP1A;Ankar;LPIN2;TAF12;BIRC2;PRMT2;TRIM24;STIL;DYRK1B
NOT transcription factor activity, sequence-specific DNA bindingRBCK1;DMRTB1;EDF1

EDF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EDF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EDF1.

PPARG; NR1H3; MEOX2; NS; ESR1; NR5A2; RXRA; TBP; MAPK6; recR

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