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EDN2

  • Official Full Name

    EDN2 endothelin 2

  • Synonyms

    EDN2; endothelin 2; endothelin-2; ET2; ET-2; preproendothelin 2; preproendothelin-2; PPET2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EDN2-12283H Recombinant Human EDN2, GST-tagged E.coli GST 21-178a.a.
Human EDN2-3055H Recombinant Human EDN2 Protein, GST-tagged Wheat Germ GST
Human EDN2-7557H Recombinant Human EDN2, His-tagged E.coli His 25-178aa
Human EDN2-6720HCL Recombinant Human EDN2 293 Cell Lysate HEK293 N/A
Human EDN2-4192HF Recombinant Full Length Human EDN2 Protein, GST-tagged In Vitro Cell Free System GST 178 amino acids
Human EDN2-8310H Native Human EDN2 N/A
Human EDN2-2027H Recombinant Human EDN2 Protein (Gln32-Arg178), N-His tagged E.coli N-His Gln32-Arg178
Rat EDN2-2010R Recombinant Rat EDN2 Protein Mammalian Cell His
Rat EDN2-1667R-B Recombinant Rat EDN2 Protein Pre-coupled Magnetic Beads HEK293
Rat EDN2-1667R Recombinant Rat EDN2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EDN2-4211Z Recombinant Zebrafish EDN2 Mammalian Cell His
Chicken EDN2-4203C Recombinant Chicken EDN2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EDN2 Related Articles
  • EDN2 Related Research Area

EDN2 involved in several pathways and played different roles in them. We selected most pathways EDN2 participated on our site, such as Class A/1 (Rhodopsin-like receptors), Direct p53 effectors, Endothelins, which may be useful for your reference. Also, other proteins which involved in the same pathway with EDN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)NMS;DRD2;ADORA2B;GPR132;LPAR2B;EDNRAB;NMBA;PNOC;ADRB1
Direct p53 effectorsCTSD;BCL2L14;FOXA1;S100A2;SCN3B;BNIP3L;ARID3A;FDXR;SMARCA4
EndothelinsEDN2;EDNRA;EDN3;EDNRB;EDN1;COL1A2;CYSLTR1;COL3A1
G alpha (q) signalling eventsTRPC3;RASGRP2;NPFF;NMB;PROK1;PROK2;TAC2;FFAR3;OXTRL
GPCR downstream signalingSCT;PNOC;PRKCHB;PTHRP2;ARHGEF25;NET1;RLN2;ABR;CCR3
GPCR ligand bindingNPFF;GNB5B;TAS2R3;CCK;PROKR1;GCGA;GPR39;OPN1LW2;CGA
Gastrin-CREB signalling pathway via PKC and MAPKANXA1A;TRPC6A;LPAR5A;KISS1;OPN4;NMU;RGS21;FPR-RS6;ABHD6B
Peptide ligand-binding receptorsCCL19A.2;NTS;NMS;PENKA;SST;PROK1;PNOCB;ZFPM2B;PNOC

EDN2 has several biochemical functions, for example, endothelin B receptor binding, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EDN2 itself. We selected most functions EDN2 had, and list some proteins which have the same functions with EDN2. You can find most of the proteins on our site.

Function Related Protein
endothelin B receptor bindingEDN3;EDN2;EDN1
hormone activityEPO;SMTLA;PTH;PRL7A1;PRL7D1;TTR;GH1;PRL6A1;IGF1

EDN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EDN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EDN2.

Mannam, VKR; Lewis, RE; et al. The fate of renal allografts hinges on responses of the microvascular endothelium. EXPERIMENTAL AND MOLECULAR PATHOLOGY 94:398-411(2013).
Chang, CY; Pasolli, HA; et al. NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. NATURE 495:98-102(2013).
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