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EFCAB6

Official Full Name

EF-hand calcium binding domain 6
Overview

This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

EFCAB6; EF-hand calcium binding domain 6; EF-hand calcium-binding domain-containing protein 6; dJ185D5.1; DJBP; FLJ23588; HSCBCIP1; KIAA1672; CAP binding protein complex interacting protein 1; DJ1 binding protein; EF hand calcium binding domain 6; DJ-1-binding protein; CAP-binding protein complex-interacting protein 1;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	EFCAB6-640HCL	Recombinant Human EFCAB6 cell lysate		N/A	Inquiry
Human	EFCAB6-1199H	Recombinant Human EFCAB6 Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Human	EFCAB6-4764H	Recombinant Human EFCAB6 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	EFCAB6-5016M	Recombinant Mouse EFCAB6 Protein	Mammalian Cell	His	Inquiry
Mouse	EFCAB6-2660M	Recombinant Mouse EFCAB6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	Efcab6-2745M	Recombinant Mouse Efcab6 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Mouse	EFCAB6-2660M-B	Recombinant Mouse EFCAB6 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
EFCAB6 Related Articles

EFCAB6 involved in several pathways and played different roles in them. We selected most pathways EFCAB6 participated on our site, such as Androgen receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFCAB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Androgen receptor signaling pathway	KAT7B;RHOB;RNF14;HTATIP;EFCAB6;NR0B2A;CTNNB2;EGFR;CREBBP

EFCAB6 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFCAB6 itself. We selected most functions EFCAB6 had, and list some proteins which have the same functions with EFCAB6. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	SYT3;SYT7B;PRRG2;ANXA6;C1RA;PCDHGA6;TPT1;PCDHGA4;TLL1

EFCAB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFCAB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFCAB6.

Zhang, ZP; Xu, HX; et al. Schistosoma japonicum calcium-binding tegumental protein SjTP22.4 immunization confers praziquantel schistosomulumicide and antifecundity effect in mice. VACCINE 30:5141-5150(2012).

Pico de Coana, Y; Parody, N; et al. Molecular cloning and characterization of Cup a 4, a new allergen from Cupressus arizonica. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 401:451-457(2010).