eftud2
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  • Official Full Name
  • elongation factor Tu GTP binding domain containing 2
  • Background
  • 116 kDa U5 small nuclear ribonucleoprotein component is a protein that in humans is encoded by the EFTUD2 gene.
  • Synonyms
  • EFTUD2; elongation factor Tu GTP binding domain containing 2; 116 kDa U5 small nuclear ribonucleoprotein component; Snrp116; Snu114; U5 snRNP specific protein; 116 kD; U5 116KD; hSNU114; U5-116 kDa; SNU114 homolog; U5 snRNP specific protein, 116 kD; U5 sn
Cat.#:EFTUD2-3110HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EFTUD2 Protein, GST-tagged
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Cat.#:EFTUD2-3147CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EFTUD2
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Cat.#:EFTUD2-10802ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EFTUD2
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Cat.#:EFTUD2-6698HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human EFTUD2 293 Cell Lysate
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Involved Pathway

EFTUD2 involved in several pathways and played different roles in them. We selected most pathways EFTUD2 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFTUD2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Spliceosome
PRPF31; HNRNPK; SRSF5; HNRPKL; SART1; SRSF7B; RBM8A; MAGOH2; HNRNPUB; SRSF5B

Protein Function

EFTUD2 has several biochemical functions, for example, GTP binding, GTPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFTUD2 itself. We selected most functions EFTUD2 had, and list some proteins which have the same functions with EFTUD2. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein TUBA8L; MXC; RAP1A; HBS1L; GNA13B; RRAS2; ARL3; MX2; LGALS6; IFT27
Function GTPase activity
Related Protein RASL10A; RAB4B; GNAQ; RAC1; RAB5AA; MXE; GNA13A; GNL2; RHOT1B; RAB2B
Function poly(A) RNA binding
Related Protein HIST1H4F; TNRC6B; MRPL4; PTBP1; EIF3I; PRPF4B; RBM14; MRPL40; TBCA; TOP3B
Function protein binding
Related Protein ZFYVE20; PSMB10; PRKRIP1; C10orf81; PAF1; PPIAL4A; IARS; NUDC; SLIRP; CPSF6
Function NOT translation elongation factor activity
Related Protein EFTUD2; GFM2

Interacting Protein

EFTUD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFTUD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFTUD2.
MYC; SNRNP40; SNW1; PRPF8; HSPB1; IK; SF3B4; DFFA; PTP4A3

EFTUD2 Related Articles

Sato, N; Maeda, M; et al. Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells. CANCER MEDICINE 4:268-277(2015).
Gandomi, SK; Parra, M; et al. Array-CGH is an effective first-tier diagnostic test for EFTUD2-associated congenital mandibulofacial dysostosis with microcephaly. CLINICAL GENETICS 87:80-84(2015).