EIF4EBP3 Protein, eukaryotic translation initiation factor 4E binding protein 3

EIF4EBP3

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EIF4EBP3

Official Full Name eukaryotic translation initiation factor 4E binding protein 3
Background This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.
Synonyms EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3; eukaryotic translation initiation factor 4E-binding protein 3; 4E BP3; eIF4E binding protein 3; Eukaryotic initiation factor 4E binding protein 3; OTTHUMP00000159879; eIF4E-binding protein 3; eukaryotic initiation factor 4E-binding protein 3; 4EBP3; 4E-BP3
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • SUMO
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Eif4ebp3-362M Recombinant Mouse Eif4ebp3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human EIF4EBP3-476H Recombinant Human EIF4EBP3 Protein (1-100 aa), His-SUMO-tagged E.coli His/SUMO
    Human EIF4EBP3-3206H Recombinant Human EIF4EBP3 Protein, GST-tagged Wheat Germ GST
    Human EIF4EBP3-6647HCL Recombinant Human EIF4EBP3 293 Cell Lysate HEK293 N/A
    Mouse EIF4EBP3-5112M Recombinant Mouse EIF4EBP3 Protein Mammalian Cell His
    Rhesus Macaque EIF4EBP3-1432R Recombinant Rhesus monkey EIF4EBP3 Protein, His-tagged Mammalian Cell His
    Zebrafish EIF4EBP3-1743Z Recombinant Zebrafish EIF4EBP3 Mammalian Cell His

    EIF4EBP3 involved in several pathways and played different roles in them. We selected most pathways EIF4EBP3 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4EBP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport GEMIN6; EIF1AY; SUMO3; PABPC1B; EIF1; EIF2B3; NCBP2; EIF4G3; EIF2B4; PABPC1L2A

    EIF4EBP3 has several biochemical functions, for example, eukaryotic initiation factor 4E binding, protein binding, translation repressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4EBP3 itself. We selected most functions EIF4EBP3 had, and list some proteins which have the same functions with EIF4EBP3. You can find most of the proteins on our site.

    Function Related Protein
    eukaryotic initiation factor 4E binding EIF4G1; OTX2; EIF4EBP3; ANGEL1; DDX3X; EIF4EBP3L; LARP1; EIF4EBP2; EIF4EBP1; HHEX
    protein binding AARSD1; C2orf63; ZFYVE27; DNM3; BAAT; LIMD1; C1orf116; USP14; KLHL3; MTTP
    translation repressor activity CIRBP; PATL2; SAMD4; PAIP2; EIF4EBP3; EIF4EBP2; IREB2; SAMD4A; TRIM71; EIF4EBP1

    EIF4EBP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4EBP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4EBP3.

    EIF4E; RPA2; Eif4e2; EIF4E2; Smad6

    Wang, ZS; Ma, XH; et al. Understanding the mechanistic roles of 30Kc6 gene in apoptosis and specific productivity in antibody-producing Chinese hamster ovary cells. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 94:1243-1253(2012).
    Rojo, F; Najera, L; et al. 4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis. CLINICAL CANCER RESEARCH 13:81-89(2007).

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