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ELP4

  • Official Full Name

    elongation protein 4 homolog

  • Overview

    Elongation protein 4 homolog (ELP4) is a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. Alternative names for ELP4 include elongator co
  • Synonyms

    ELP4; elongation protein 4 homolog (S. cerevisiae); C11orf19, chromosome 11 open reading frame 19; elongator complex protein 4; PAXNEB; hELP4; PAX6 neighbor gene protein; PAX6NEB; C11orf19; dJ68P15A.1; FLJ20498;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ELP4-623H Recombinant Human elongator acetyltransferase complex subunit 4, His-tagged E.coli His
Human ELP4-12425H Recombinant Human ELP4, His-tagged E.coli His C-term-299a.a.
Human ELP4-3265H Recombinant Human ELP4 Protein, GST-tagged Wheat Germ GST
Human ELP4-6615HCL Recombinant Human ELP4 293 Cell Lysate HEK293 N/A
Human ELP4-4560H Recombinant Human ELP4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ELP4-4227HF Recombinant Full Length Human ELP4 Protein, GST-tagged In Vitro Cell Free System GST 535 amino acids
Mouse ELP4-5156M Recombinant Mouse ELP4 Protein Mammalian Cell His
Mouse ELP4-2758M-B Recombinant Mouse ELP4 Protein Pre-coupled Magnetic Beads HEK293
Mouse Elp4-2806M Recombinant Mouse Elp4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ELP4-2758M Recombinant Mouse ELP4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ELP4-2408Z Recombinant Zebrafish ELP4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ELP4 Related Articles

ELP4 involved in several pathways and played different roles in them. We selected most pathways ELP4 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesCHD4A;USP22;TADA2B;KDM4D;AEBP2;CSRP2BP;ACTL6A;SMARCE1;KDM5A
Chromatin organizationPBRM1L;SUDS3;MTA3;ZZZ3;ARID4A;SMARCC1B;KDM5C;RUVBL2;ANO9A
HATs acetylate histonesELP2;KAT7B;PAX3A;VPS72;CAPNS2;ING4;ELP3;KIAA1267;MSL2B

ELP4 has several biochemical functions, for example, contributes_to RNA polymerase II core binding, contributes_to histone acetyltransferase activity, phosphorylase kinase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ELP4 itself. We selected most functions ELP4 had, and list some proteins which have the same functions with ELP4. You can find most of the proteins on our site.

Function Related Protein
contributes_to RNA polymerase II core bindingIKBKAP;ELP2;ELP4;ELP3
contributes_to histone acetyltransferase activityTADA2A;EPC1;SUPT7L;SAP130;TAF9;KAT2A;KAT5;TAF5L;SUPT3H
phosphorylase kinase regulator activityELP4;ELP3;PRKAG2;IKBKAP
protein bindingMYEF2;TAF7L;GIMAP7;IRF5;EIF4EBP3L;SPTBN1;CAMSAP1L1;NCAPH2;FBXW7

ELP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELP4.

IKBKAP; ELP5; CBX6; ELP6; ELP2; ELP3

Hughes, LA; Gaston, J; et al. Electrospun fiber constructs for vocal fold tissue engineering: Effects of alignment and elastomeric polypeptide coating. ACTA BIOMATERIALIA 13:111-120(2015).
Gkampeta, A; Fidani, L; et al. Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population. EPILEPSY RESEARCH 108:1734-1739(2014).
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