emd
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  • Official Full Name
  • EMD emerin
  • Background
  • Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
  • Synonyms
  • EMD; emerin; Emery Dreifuss muscular dystrophy; LEM domain containing 5; LEMD5; STA; EDMD
Cat.#:EMD-3273HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EMD Protein, GST-tagged
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Cat.#:EMD-28289THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human EMD
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Cat.#:EMD-5170MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EMD Protein
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Cat.#:EMD-2091RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EMD Protein
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Cat.#:EMD-6612HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human EMD 293 Cell Lysate
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Involved Pathway

EMD involved in several pathways and played different roles in them. We selected most pathways EMD participated on our site, such as Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, which may be useful for your reference. Also, other proteins which involved in the same pathway with EMD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hypertrophic cardiomyopathy (HCM)
ITGA9; DMD; ITGB3; ITGA2B; SGCG; LAMA2; CACNG8; MYL2; IGF1; CACNG1
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
AASS; ITGA9; CACNB2; ITGB5; CACNB4; ITGAV; RYR2; CACNG6; ITGA1; ITGB8
Dilated cardiomyopathy
CACNB4; DES; CACNG2; SGCD; CACNG8; Adcy4; ITGA2; ACTB; SGCG; ITGA7

Protein Function

EMD has several biochemical functions, for example, actin binding, beta-tubulin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMD itself. We selected most functions EMD had, and list some proteins which have the same functions with EMD. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein VASP; PARVG; MYH11A; SSH2; SHANK3; PHACTR4B; TRPV4; TPM4; DBNL; NRAP
Function beta-tubulin binding
Related Protein MAP1S; RGS2; IFT74; CASC1; UXT; CCT5; NDEL1; SLC6A2; TRPV4; RANBP10
Function protein binding
Related Protein BOK; KRTAP10-8; LRRFIP2; MYO10; KRTAP10-9; FUT11; MED23; ZNHIT3; MAST2; TRIM44

Interacting Protein

EMD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMD here. Most of them are supplied by our site. Hope this information will be useful for your research of EMD.
FATE1; CTNNB1; BCLAF1; SYNE2; TRIM42; 80125

EMD Related Articles

van den Heuvel, MM; Verheij, M; et al. NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy. JOURNAL OF TRANSLATIONAL MEDICINE 13:-(2015).
Elez, E; Kocakova, I; et al. Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients with KRAS wild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial. ANNALS OF ONCOLOGY 26:132-140(2015).