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EPN2

  • Official Full Name

    epsin 2

  • Overview

    This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
  • Synonyms

    EPN2; epsin 2; epsin-2; EHB21; Eps15 binding protein; KIAA1065; EPS-15-interacting protein 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EPN2-3417H Recombinant Human EPN2 Protein, GST-tagged Wheat Germ GST
Human EPN2-6580HCL Recombinant Human EPN2 293 Cell Lysate HEK293 N/A
Human EPN2-3912H Recombinant Human EPN2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EPN2-4393HF Recombinant Full Length Human EPN2 Protein, GST-tagged In Vitro Cell Free System GST 584 amino acids
Mouse Epn2-963M Recombinant Mouse Epn2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Chicken EPN2-2017C Recombinant Chicken EPN2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EPN2 Related Articles

EPN2 involved in several pathways and played different roles in them. We selected most pathways EPN2 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisGRK4;FAM21C;CHMP4B;CAPZB;CDC42L;RAB7;AP2M1B;ADRB3B;EPS15

EPN2 has several biochemical functions, for example, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPN2 itself. We selected most functions EPN2 had, and list some proteins which have the same functions with EPN2. You can find most of the proteins on our site.

Function Related Protein
lipid bindingACBD5;BPIFA3;SH3GL3;MTTP;GPIHBP1;STARD10;S100A13;ACBD4;APOL4
protein bindingTLR6;CCDC60;GZMA;ROCK1;CBLN3;SMARCA4;DNMT3L;IL32;RRM1

EPN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPN2.

GTSE1

Khanna, R; Li, Q; et al. 'Fractional Recovery' Analysis of a Presynaptic Synaptotagmin 1-Anchored Endocytic Protein Complex. PLOS ONE 1:-(2006).
Sorkina, T; Miranda, M; et al. RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. JOURNAL OF NEUROSCIENCE 26:8195-8205(2006).
  • Q&As
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