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EREG

  • Official Full Name

    epiregulin

  • Overview

    Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene.
  • Synonyms

    Epiregulin; EPR; EREG; ER; Ereg; epiregulin; proepiregulin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Fc
  • GST
  • His
  • His|GST
  • His|T7
  • SUMO
  • Met
  • N/A
  • N
  • hFc
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EREG-235H Recombinant Human EREG protein E.coli N/A 49
Human EREG-28692TH Recombinant Human EREG E.coli N/A 49 amino acids
Human EREG-3465H Recombinant Human EREG Protein, GST-tagged Wheat Germ GST
Human EREG-562H Active Recombinant Human EREG protein(Val63-Leu108), hFc-tagged HEK293 N-hFc Val63-Leu108
Human EREG-1998H Recombinant Human EREG protein, His & GST-tagged E.coli His/GST Val30~Val169 (Accession # O14944)
Human EREG-1868HCL Recombinant Human EREG cell lysate Human Cell N/A
Human EREG-004H Active Recombinant Human EREG Protein E. coli
Human EREG-023H Active Recombinant Human EREG Protein E. coli
Human EREG-4564HF Recombinant Full Length Human EREG Protein, GST-tagged In Vitro Cell Free System GST 169 amino acids
Human EREG-1438H Recombinant Human EREG Protein, His-tagged E.coli N-His Val63-Leu108
Human EREG-2869H Recombinant Human EREG protein, His-SUMO-tagged E.coli His-SUMO 60-119aa
Human EREG-125E Active Recombinant Human EREG Protein (50 aa) E.coli 50
Mouse Ereg-576M Active Recombinant Mouse Ereg, Fc tagged HEK293 Fc Val 56-Leu 101
Mouse Ereg-595M Active Recombinant Mouse Ereg E.coli Met Val56-Leu101
Mouse Ereg-198M Recombinant Mouse Epiregulin E.coli N/A
Mouse EREG-1871MCL Recombinant Mouse EREG cell lysate Human Cell N/A
Rat Ereg-1999R Recombinant Rat Ereg protein, His & T7-tagged E.coli His/T7 Met1~Val162 (Accession# Q9Z0L5)
Homo sapiens (Human) RFL19531HF Recombinant Full Length Human Proepiregulin(Ereg) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-169)
Chicken EREG-1077C Recombinant Chicken EREG Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EREG Related Articles
  • EREG Related Research Area

EREG involved in several pathways and played different roles in them. We selected most pathways EREG participated on our site, such as ErbB signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EREG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayTGFA;MAP2K7;PRKCB;SOS1;NCK2B;PAK6B;CBLC;NRG2B;MAP2K4A

EREG has several biochemical functions, for example, epidermal growth factor receptor binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EREG itself. We selected most functions EREG had, and list some proteins which have the same functions with EREG. You can find most of the proteins on our site.

Function Related Protein
epidermal growth factor receptor bindingHBEGF;SNX2;CBLC;AGR2;FAM83B;SHC1;HBEGFB;ATXN2;MS4A1
growth factor activityGPI1;FGF20B;CLEC11A;PDGFD;CSF1B;COL20A1;CSF2;FGF13A;IGF2B
protein bindingVCL;RRM1;NADSYN1;RPL12;CAMK2D;EPRS;DDX5;ELK1;MAPRE1

EREG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EREG here. Most of them are supplied by our site. Hope this information will be useful for your research of EREG.

Addison, JB; Koontz, C; et al. KAP1 Promotes Proliferation and Metastatic Progression of Breast Cancer Cells. CANCER RESEARCH 75:344-355(2015).
Takahashi, N; Yamada, Y; et al. Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer. BRITISH JOURNAL OF CANCER 110:2716-2727(2014).
  • Q&As
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