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ERC2

Official Full Name

ELKS/RAB6-interacting/CAST family member 2
Overview

Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Synonyms

ERC2; ELKS/RAB6-interacting/CAST family member 2; CAST; CAST1; ELKSL; Spc110; SPBC110; ERC protein 2; cytomatrix protein p110; CAZ-associated structural protein;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ERC2-12520H	Recombinant Human ERC2, GST-tagged	E.coli	GST	768-827a.a.	$319 / 25ug
Human	ERC2-6569HCL	Recombinant Human ERC2 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	ERC2-5283M	Recombinant Mouse ERC2 Protein	Mammalian Cell	His		Inquiry
Mouse	ERC2-2841M	Recombinant Mouse ERC2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	ERC2-2841M-B	Recombinant Mouse ERC2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ERC2-2136R	Recombinant Rat ERC2 Protein	Mammalian Cell	His		Inquiry
Rat	ERC2-1793R	Recombinant Rat ERC2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	ERC2-1793R-B	Recombinant Rat ERC2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
ERC2 Related Articles

ERC2 involved in several pathways and played different roles in them. We selected most pathways ERC2 participated on our site, such as Diurnally regulated genes with circadian orthologs, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Diurnally regulated genes with circadian orthologs	CEBPB;STBD1;PURA;KLF9;EIF4G2;CRY2;ZFR;NR1D2;CBX3

ERC2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERC2 itself. We selected most functions ERC2 had, and list some proteins which have the same functions with ERC2. You can find most of the proteins on our site.

Function	Related Protein
protein binding	LMF2;SF3A2;POLM;SNCG;MRPS6;MAGEB18;SLC30A2;EIF4EBP3;ODF1

ERC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERC2.

MYB; IQCB1; Cd2ap

Arai, E; Sakamoto, H; et al. Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome. INTERNATIONAL JOURNAL OF CANCER 135:1330-1342(2014).

Bruin, SC; de Ronde, JJ; et al. Selection of Patients for Hepatic Surgery of Colorectal Cancer Liver Metastasis Based on Genomic Aberrations. ANNALS OF SURGICAL ONCOLOGY 20:S560-S569(2013).