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TFAP2C

  • Official Full Name

    transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

  • Overview

    The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
  • Synonyms

    TFAP2C; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP 2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma; AP2 GAMMA; ERF1; estrogen receptor factor 1; hAP 2g; TFA;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TFAP2C-7347H Recombinant Human TFAP2C, His tagged E.coli His
Human TFAP2C-1766HCL Recombinant Human TFAP2C cell lysate N/A
Mouse Tfap2c-6375M Recombinant Mouse Tfap2c Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish TFAP2C-1875Z Recombinant Zebrafish TFAP2C Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TFAP2C Related Research Area

TFAP2C involved in several pathways and played different roles in them. We selected most pathways TFAP2C participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TFAP2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TFAP2C has several biochemical functions, for example, DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFAP2C itself. We selected most functions TFAP2C had, and list some proteins which have the same functions with TFAP2C. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF83;RXRGB;HDGF;CHD6;APEX1;LASS4;POU3F2B;PMS1;ZFP239
RNA polymerase II distal enhancer sequence-specific DNA bindingH3F3A;SPI1;SFPQ;NR5A1;ESRRB;SIX3;H3F3B;FLI1;BACH1
RNA polymerase II regulatory region sequence-specific DNA bindingHES6;ZFP551;ONECUT3;SP1;H2AFY2;CDX1B;ESX1;EOMES;FERD3L
core promoter bindingAGO1;IRF9;E2F3;NKX3-1;FOXP3;NPAS2;PYDC3;GATA1;XBP1
protein bindingKIF3B;CENPA;SIX1;RIPK4;KHK;PCSK2;RBMX;XAGE3;FAM49B
protein dimerization activityANO7;HES6;CLOCKB;STAT3;MTOR;MEF2CA;HES2;HIF1AL2;LYL1
transcription factor activity, sequence-specific DNA bindingHOXB6A;NME2;PAX6;LBX1;GCM1;GATAD2AB;ZNF263;PHTF1;ZBTB17
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingEPAS1;KLF15;HLTF;NR2E1;DDIT3;HOXC11;FIGLA;RFX4;FOSB
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific bindingHSF1;HMGA2;KLF16;PRDM1;OVOL1;BACH1;PROX1;GATA3;ATF7

TFAP2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFAP2C here. Most of them are supplied by our site. Hope this information will be useful for your research of TFAP2C.

UBE2I; human_frem2_promoter_region_probe; RARA; CITED2; EYA2; IKBKB; LDLRAD4; LAMA5; ACTN4; NR1I2

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