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EXOSC10

  • Official Full Name

    Exosome Component 10

  • Overview

    Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which is part of the exosome complex and is an autoantigen is patients with certain auto immune diseases, most notably scleromyositis.
  • Synonyms

    EXOSC10; exosome component 10; p3; p4; RRP6; PMSCL; Rrp6p; PM-Scl; PMSCL2; PM/Scl-100; OTTHUMP00000002176; OTTHUMP00000002177; autoantigen PM-SCL; autoantigen PM/Scl 2; polymyositis/scleroderma autoantigen 100 kDa; polymyositis/scleroderma autoantigen 2 (100kD); polymyositis/scleroderma autoantigen 2, 100kDa; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen; EXOSX_HUMAN; p2; PM Scl; PM/Scl 100;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EXOSC10-12594H Recombinant Human EXOSC10, GST-tagged E.coli GST C-term-300a.a.
Human EXOSC10-26640TH Recombinant Human EXOSC10, His-tagged His
Human EXOSC10-5391H Recombinant Human EXOSC10 protein, His-tagged Insect Cell His
Human EXOSC10-183H Recombinant human EXOSC10 E.coli His
Human EXOSC10-3567H Recombinant Human EXOSC10 Protein, GST-tagged Wheat Germ GST
Human EXOSC10-6504HCL Recombinant Human EXOSC10 293 Cell Lysate HEK293 N/A
Human EXOSC10-3475H Recombinant Human EXOSC10 protein, His-tagged E.coli His 586-885 aa
Human EXOSC10-4426HF Recombinant Full Length Human EXOSC10 Protein, GST-tagged In Vitro Cell Free System GST 885 amino acids
Human EXOSC10-2815H Recombinant Human EXOSC10 protein(691-850 aa), C-His-tagged E. coli C-His 691-850 aa
Mouse EXOSC10-5381M Recombinant Mouse EXOSC10 Protein Mammalian Cell His
Mouse EXOSC10-2902M-B Recombinant Mouse EXOSC10 Protein Pre-coupled Magnetic Beads HEK293
Mouse EXOSC10-2902M Recombinant Mouse EXOSC10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EXOSC10-11312Z Recombinant Zebrafish EXOSC10 Mammalian Cell His
Chicken EXOSC10-1995C Recombinant Chicken EXOSC10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

EXOSC10 involved in several pathways and played different roles in them. We selected most pathways EXOSC10 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOSC10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA degradationDIS3L;PABPC1L;CNOT6;BTG4;CNOT10;MPHOSPH6;C1D;CNOT4;PABPC4

EXOSC10 has several biochemical functions, for example, 3-5 exonuclease activity, exoribonuclease activity, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOSC10 itself. We selected most functions EXOSC10 had, and list some proteins which have the same functions with EXOSC10. You can find most of the proteins on our site.

Function Related Protein
3-5 exonuclease activityERI1;POLE;EXD2;TREX1;REXO2;EXOSC10;MRE11A;REV3L;WRN
exoribonuclease activityEXOSC10;CNOT7;CNOT6
nucleotide bindingMYH8;POLDIP3;ABCA4A;HPRT1;MVDA;MTHFSD;MXA;RAD51L3;BMPR2B
poly(A) RNA bindingDDX21;RPUSD2;ROCK2;HNRNPA0;OASL;KIAA0020;UTP23;PKM;RPL22
protein bindingTAG-260;EFNA1;ERP27;ZW10;AEN;CLEC18A;HNRNPUL1;SERPINF2;FAM46B

EXOSC10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOSC10 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOSC10.

EXOSC2; MPHOSPH6; EXOSC5; EXOSC4; DIS3

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