EXT1
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Official Full Name
exostosin 1
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Human
- Mouse
- Mus musculus (Mouse)
- Papio anubis (Olive baboon)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | EXT1-3583H | Recombinant Human EXT1 Protein, GST-tagged | Wheat Germ | GST |
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| Human | EXT1-6497HCL | Recombinant Human EXT1 293 Cell Lysate | HEK293 | N/A |
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| Human | EXT1-3274H | Recombinant Human EXT1 protein, His-tagged | E.coli | His | 36-330 aa | |
| Human | EXT1-412H | Recombinant Human EXT1 Protein, His-tagged | E.coli | His | Cys334~Arg549 | |
| Human | EXT1-4446HF | Recombinant Full Length Human EXT1 Protein, GST-tagged | In Vitro Cell Free System | GST | 746 amino acids |
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| Human | EXT1-2682H | Recombinant Human EXT1 protein, His-tagged | E.coli | His | 435-573 aa | |
| Mouse | EXT1-5391M | Recombinant Mouse EXT1 Protein | Mammalian Cell | His |
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| Mouse | EXT1-2908M-B | Recombinant Mouse EXT1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | EXT1-2908M | Recombinant Mouse EXT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Bos taurus (Bovine) | RFL27068BF | Recombinant Full Length Bovine Exostosin-1(Ext1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-746) |
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| Mus musculus (Mouse) | RFL18736MF | Recombinant Full Length Mouse Exostosin-1(Ext1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-746) |
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| Papio anubis (Olive baboon) | RFL32034PF | Recombinant Full Length Papio Anubis Exostosin-1(Ext1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-746) |
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| Rhesus Macaque | EXT1-1524R | Recombinant Rhesus monkey EXT1 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | EXT1-1349R-B | Recombinant Rhesus Macaque EXT1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | EXT1-1349R | Recombinant Rhesus Macaque EXT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
- EXT1 Related Articles
- EXT1 Related Research Area
EXT1 involved in several pathways and played different roles in them. We selected most pathways EXT1 participated on our site, such as Glycosaminoglycan biosynthesis - heparan sulfate / heparin, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycosaminoglycan biosynthesis - heparan sulfate / heparin | HS6ST3;HS6ST3B;HS2ST1A;HS6ST1;NDST1;EXTL2;EXT1B;HS6ST1B;HS2ST1 |
| Metabolic pathways | NDUFB10;ASPA;PMVK;CEL.1;LIPF;PRPS1B;NME2B.1;MTHFD1L;ATP5I |
EXT1 has several biochemical functions, for example, N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity, acetylglucosaminyltransferase activity, glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EXT1 itself. We selected most functions EXT1 had, and list some proteins which have the same functions with EXT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity | EXT1;EXT2;EXT1A;EXT1C;EXT1B |
| acetylglucosaminyltransferase activity | XYLT1;GTDC2;HEXA;POMGNT2;OGT;EXT1;C3orf39;XYLT2;MGAT1 |
| glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity | EXT1;EXT1A;EXT1B;EXTL1;EXT1C;EXT2 |
| glucuronosyltransferase activity | UGT1A1;UGT1B1;UGT2B6;LARGE;UGT2B7;UGT1B3;UGT5C3;UGT8;UGT1B7 |
| heparan sulfate N-acetylglucosaminyltransferase activity | EXT1;EXT2 |
| metal ion binding | DPEP3;MAP3K2;ZXDB;GNAL;GLRX3;ATP2A2A;PPARG;BIRC5;OVCH2 |
| protein heterodimerization activity | ZBTB1;HNF1B;TXLNG;SRI;POLA1;SOX15;Itgam&Itgb2;VEGFA;CUL3 |
| protein homodimerization activity | VIL1;TPD52;SNX9;CRYAB;FIGF;NOS1;INHBB;SMAD1;NTSR1 |
| transferase activity, transferring glycosyl groups | GXYLT1B;B3GNTL1;MGAT3A;UGT5G1;EXT1C;PNP4A;PNP5B;UGT8A;B3GNT2A |
EXT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXT1.
MYH1; CNTF; OSTF1; fdhF; Kif2c
- Q&As
- Reviews
Q&As (7)
Ask a questionEXT1 forms a complex with EXT2, another glycosyltransferase, for its stability and proper function.
Therapeutic strategies might involve targeted therapies to correct heparan sulfate chain synthesis or modulate affected signaling pathways.
EXT1 is ubiquitously expressed but shows higher expression in certain tissues such as cartilage.
Mutations in EXT1 result in shortened heparan sulfate chains, affecting their function and interaction with signaling molecules.
Dysregulation of EXT1 affects pathways such as Hedgehog, Wnt, and FGF signaling, leading to abnormal growth and development.
EXT1 is involved in the elongation of heparan sulfate chains, a critical component for cell signaling, adhesion, and growth.
Mutations in EXT1 are associated with hereditary multiple exostoses (HME), a condition characterized by the formation of bony outgrowths.
Customer Reviews (3)
Write a reviewProduct delivered on time.
Highly recommend this product.
Very effective, good quality.
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