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ECM1

  • Official Full Name

    extracellular matrix protein 1

  • Overview

    This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
  • Synonyms

    ECM1; extracellular matrix protein 1; secretory component p85;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ECM1-315H Active Recombinant Human ECM1, His-tagged Mammalian cells His
Human ECM1-3037H Recombinant Human ECM1 Protein, GST-tagged Wheat Germ GST
Human ECM1-691H Recombinant Human ECM1, His tagged Human Cell His
Human ECM1-12269H Recombinant Human ECM1, GST-tagged E.coli GST C-term-300a.a.
Human ECM1-1621HFL Recombinant Full Length Human ECM1 Protein, C-Flag-tagged Mammalian cells Flag
Human ECM1-925H Recombinant Human ECM1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ECM1-1772H Recombinant Human ECM1 protein, His-tagged E.coli His Ala20~Glu540
Human ECM1-2351H Recombinant Human ECM1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ECM1-799H Recombinant Human ECM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ECM1-1401H Recombinant Human ECM1 Protein, His-tagged E.coli N-His His150-Tyr405
Human ECM1-3579H Recombinant Human ECM1 protein(20-241 aa), His-tagged E.coli N-His 20-241 aa
Human ECM1-2024H Recombinant Human ECM1 Protein (Met241-Glu540), N-His tagged E.coli N-His Met241-Glu540
Human ECM1-799H-B Recombinant Human ECM1 Protein Pre-coupled Magnetic Beads HEK293
Human ECM1-4172HF Recombinant Full Length Human ECM1 Protein, GST-tagged In Vitro Cell Free System GST 540 amino acids
Mouse Ecm1-363M Active Recombinant Mouse Ecm1 protein, His-tagged Mammalian cells His Ala20-Glu559
Mouse Ecm1-4027M Active Recombinant Mouse Ecm1 protein, His-tagged HEK293 His Met1-Glu559
Mouse ECM1-2036MCL Recombinant Mouse ECM1 cell lysate Human Cell N/A
Mouse Ecm1-2628M-B Recombinant Mouse Ecm1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Ecm1-2720M Recombinant Mouse Ecm1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Ecm1-2628M Recombinant Mouse Ecm1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ecm1-690M Recombinant Mouse Ecm1 Protein, His/GST-tagged E.coli His/GST Ala20~Glu434
Rat Ecm1-1122R Recombinant Rat Ecm1 Protein, His-tagged HEK293 His
Rat ECM1-2006R Recombinant Rat ECM1 Protein Mammalian Cell His
Rat ECM1-1663R Recombinant Rat ECM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ECM1-1663R-B Recombinant Rat ECM1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ECM1 Related Articles
  • ECM1 Related Research Area

ECM1 involved in several pathways and played different roles in them. We selected most pathways ECM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ECM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ECM1 has several biochemical functions, for example, enzyme binding, interleukin-2 receptor binding, laminin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ECM1 itself. We selected most functions ECM1 had, and list some proteins which have the same functions with ECM1. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingTARBP2;TNKS2;TBP;STUB1;RCOR1;WWOX;UBE2L3;CYP2A4;RFC5
interleukin-2 receptor bindingTIMM50;IL21;GATA3;Il2;ECM1
laminin bindingACHE;NCL;ITGB1;RPSA;ITGA7;LYPD5;TINAGL1;ADAM9;ITGA9
protease bindingRNF139;IL1R1;CD28;CCBE1;FAP;MBL1;TRP53;CHL1;INS
protein C-terminus bindingMLLT4;ERCC6;HIC2;TRIM3;MPDZ;MRE11A;SREBF2;CACNA1B;VPS36
protein bindingSEC61G;BRPF1;LARP2;FANCD2;TNNI3K;ARFGAP3;SHROOM2;MOB1A;KRTAP12-4
signal transducer activityOR115-6;GHRHR2;TRADD;PPP5C;TAS2R117;DKK1;OLFR867;PLCD1A;CSPG4

ECM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ECM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ECM1.

SRPK1; BNIP3L; ATN1; pyrF; CPTP; q7arb3_yerpe; q7ckb2_yerpe; q8ckn0_yerpe; RERE; IRAK3

Lee, KM; Nam, K; et al. Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling. BREAST CANCER RESEARCH 16:-(2014).
Plevy, S; Silverberg, MS; et al. Combined Serological, Genetic, and Inflammatory Markers Differentiate Non-IBD, Crohn's Disease, and Ulcerative Colitis Patients. INFLAMMATORY BOWEL DISEASES 19:1139-1148(2013).
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