Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

EFNB3

  • Official Full Name

    ephrin-B3

  • Overview

    EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function.The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
  • Synonyms

    EFNB3; ephrin-B3; EPLG8; LERK 8; Ephrin B3; eph-related receptor tyrosine kinase ligand 8; EPH-related receptor transmembrane ligand ELK-L3; EFL6; LERK8;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • C
  • Fc
  • His
  • hFc
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EFNB3-713H Active Recombinant Human EFNB3 protein, Fc/His-Tagged, Biotinylated Insect Cells C-Fc/His Leu28-Ser224
Human EFNB3-1612H Recombinant Human EFNB3 Mammalian cells N/A
Human EFNB3-153H Recombinant Human Ephrin-B3 E.coli N/A
Human EFNB3-6965H Recombinant Human Ephrin-B3, His-tagged E.coli His 28-226aa
Human EFNB3-3106H Recombinant Human EFNB3 Protein, His-tagged E.coli His
Human EFNB3-4398H-B Recombinant Human EFNB3 Protein Pre-coupled Magnetic Beads HEK293
Human EFNB3-4398H Recombinant Human EFNB3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Efnb3-957M Active Recombinant Mouse Efnb3 Protein, Fc Chimera Mammalian cells Fc
Mouse EFNB3-5035M Recombinant Mouse EFNB3 Protein Mammalian Cell His
Mouse Efnb3-984M Active Recombinant Mouse Efnb3 protein, hFc-tagged HEK293 hFc Met1-Ala227
Mouse Efnb3-985M Recombinant Mouse Efnb3 Protein, His-tagged HEK293 His
Mouse Efnb3-30M Recombinant Mouse Efnb3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse EFNB3-2337M Recombinant Mouse EFNB3 Protein (28-227 aa), His-tagged Yeast His 28-227 aa
Mouse Efnb3-30M-B Recombinant Mouse Efnb3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Efnb3-2838M Recombinant Mouse Efnb3 protein, His-tagged E.coli His 28-227aa
Rat Efnb3-8716R Active Recombinant Rat Efnb3 protein, hFc-tagged HEK293 hFc Met1-Ser224
Rat Efnb3-8717R Active Recombinant Rat Efnb3 protein, His-tagged HEK293 His Met1-Ser224
Rat EFNB3-1264RCL Recombinant Rat EFNB3 cell lysate Human Cell N/A
Rat EFNB3-471R Recombinant Rat EFNB3 Protein (28-227 aa), His-tagged E.coli His 28-227 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EFNB3 Related Articles
  • EFNB3 Related Research Area

EFNB3 involved in several pathways and played different roles in them. We selected most pathways EFNB3 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFNB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceRANBP9;ROBO1;LOC608458;LRRC4C;KALRN;RNF8;KDR;EPHA3;CD24
Developmental BiologyITGB3A;RNF8;KIF4;TCF12;MED18;EPHB4A;EFNA1B;COL9A1A;CSNK2B
EPH-Ephrin signalingMYL12B;ACTR2B;EFNA1A;KALRN;EFNB2;EPHB4A;EFNA5;EPHA4A;EFNA2A
EPH-ephrin mediated repulsion of cellsEFNA2A;EPHA4A;EFNA1B;AP2S1;EFNA1;EPHA2A;EFNA2;EFNB2A;EPHB4B
EPHB forward signalingEFNB2;ITSN1;EFNB3;GRB7;EFNA5;EFNB1
EPHB-mediated forward signalingARPC3;EPHB4B;ARPC1B;ACTR2;ARPC1A;EFNB3B;KALRNB;ARHGEF28;ARPC5
Ephrin signalingEPHB4B;EFNB2A;MYL12A;EFNB3B;EFNB3;EPHB4A;EPHB3A;EFNB1;EFNB2

EFNB3 has several biochemical functions, for example, ephrin receptor binding, transmembrane-ephrin receptor activity, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EFNB3 itself. We selected most functions EFNB3 had, and list some proteins which have the same functions with EFNB3. You can find most of the proteins on our site.

Function Related Protein
ephrin receptor bindingEFNA3;SIPA1L1;EFNB1;SRC;SHC1;NTRK1;FYN;EFNB2B;Anks1
transmembrane-ephrin receptor activityEPHB1;EPHA5;EPHA10;EPHA4;EFNA3;EPHB2;EFNB3;EFNA4;EPHA1
virus receptor activityRPSA;EFNB2;LDLR;TNFRSF14;HAVCR1;ITGB1;ITGA5;ITGB6;ITGB5

EFNB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFNB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFNB3.

YWHAZ; TCEB1; P2RX7; AATF

Baniwal, SK; Chimge, NO; et al. Prolactin-Induced Protein (PIP) Regulates Proliferation of Luminal A Type Breast Cancer Cells in an Estrogen-Independent Manner. PLOS ONE 8:-(2013).
Steffen, DL; Xu, K; et al. Henipavirus Mediated Membrane Fusion, Virus Entry and Targeted Therapeutics. VIRUSES-BASEL 4:280-308(2012).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All EFNB3 Products

Required fields are marked with *

My Review for All EFNB3 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends