EGFL7
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Official Full Name
EGF-like-domain, multiple 7
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Overview
This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants that encode the same protein. -
Synonyms
EGFL7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; ZNEU1; EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGF-like protein 7; EGFL 7; EGFL7_HUMAN; Epidermal growth factor like domain protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple EGF-like domains protein 7; Multiple epidermal growth factor like domain protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1 protein; NOTCH4 like protein; NOTCH4-like protein; RP11 251M1.2; UNQ187/PRO1449; Vascular endothelial statin; VE statin; VE-statin; ZNEU 1; OTTHUMP00000022597; OTTHUMP00000022598; OTTHUMP00000022599; NEU1; RP11-251M1.2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Insect Cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- EGFL7 Related Articles
- EGFL7 Related Research Area
EGFL7 involved in several pathways and played different roles in them. We selected most pathways EGFL7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EGFL7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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EGFL7 has several biochemical functions, for example, Notch binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EGFL7 itself. We selected most functions EGFL7 had, and list some proteins which have the same functions with EGFL7. You can find most of the proteins on our site.
Function | Related Protein |
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Notch binding | AAK1;JAG2B;GALNT11;JAG1A;ADAM17;JAG2;EGFL7;JAG1;NOTCH4 |
calcium ion binding | SLC25A12;LTBP2;PLCD1;MAN1B1;FAT3A;EFCAB7;AKR1C1;PNLIPRP1;JAG1A |
EGFL7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EGFL7 here. Most of them are supplied by our site. Hope this information will be useful for your research of EGFL7.
LMP1; ul31_ebvb9; proS; katG; GFI1B; q81sn0_bacan; mrcA; hscA; SMARCD1; q9wmx2-pro_0000037541; Cenpe; Eef1a1; Smn1; CLTC; LOXL2
- Q&As
- Reviews
Q&As (5)
Ask a questionTherapeutic interventions may involve targeting EGFL7 to modulate angiogenesis. This could be achieved through the development of drugs or therapies that either inhibit or enhance EGFL7 activity, depending on the clinical context.
EGFL7 interacts with various proteins involved in the angiogenic pathway, including growth factors and receptors. Understanding these interactions is essential for deciphering its role in angiogenesis.
Some research suggests that EGFL7 expression levels may have prognostic value in predicting outcomes for cancer patients. Higher or lower expression levels could be indicative of disease severity or response to treatment.
The regulation of EGFL7 expression is complex and varies in different conditions. Understanding the regulatory mechanisms is crucial for developing targeted therapies that modulate EGFL7 expression appropriately.
As of now, there are no widely accepted therapies specifically targeting EGFL7. However, ongoing research may lead to the development of targeted therapies in the future.
Customer Reviews (3)
Write a reviewThese resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.
Their collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.
The manufacturer's support is crucial for researchers using EGFL7 protein in trials.
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