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EGFL7

  • Official Full Name

    EGF-like-domain, multiple 7

  • Overview

    This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants that encode the same protein.
  • Synonyms

    EGFL7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; ZNEU1; EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGF-like protein 7; EGFL 7; EGFL7_HUMAN; Epidermal growth factor like domain protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple EGF-like domains protein 7; Multiple epidermal growth factor like domain protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1 protein; NOTCH4 like protein; NOTCH4-like protein; RP11 251M1.2; UNQ187/PRO1449; Vascular endothelial statin; VE statin; VE-statin; ZNEU 1; OTTHUMP00000022597; OTTHUMP00000022598; OTTHUMP00000022599; NEU1; RP11-251M1.2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EGFL7-3115H Recombinant Human EGFL7 Protein, GST-tagged Wheat Germ GST
Human EGFL7-3077H Active Recombinant Human EGFL7 protein(Tyr24-Ser273), His-tagged Insect Cells N-His Tyr24-Ser273
Human EGFL7-649HCL Recombinant Human EGFL7 cell lysate Insect Cell N/A
Human EGFL7-1694H Recombinant Human EGFL7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EGFL7-1873H Recombinant Human EGFL7 protein, His & T7-tagged E.coli His/T7 Tyr24~Ser273 (Accession # Q9UHF1)
Human EGFL7-809H-B Recombinant Human EGFL7 Protein Pre-coupled Magnetic Beads HEK293
Human EGFL7-2127H Recombinant Human EGFL7 Protein (Tyr24-Ser273), N-His tagged E.coli N-His Tyr24-Ser273
Human EGFL7-1375H Recombinant Human EGFL7 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human EGFL7-4256HF Recombinant Full Length Human EGFL7 Protein, GST-tagged In Vitro Cell Free System GST 24-273 amino acids
Human EGFL7-1545HFL Recombinant Full Length Human EGFL7 Protein, C-Flag-tagged Mammalian cells Flag
Human EGFL7-809H Recombinant Human EGFL7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Egfl7-4033M Recombinant Mouse Egfl7 protein, His-tagged Insect Cells His Glu22-Leu275
Mouse EGFL7-565MCL Recombinant Mouse EGFL7 cell lysate Insect Cell N/A
Mouse Egfl7-2759M Recombinant Mouse Egfl7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Egfl7-7391M Recombinant Mouse Egfl7 Protein, His-tagged Insect Cell His
Mouse Egfl7-1874M Recombinant Mouse Egfl7 protein, His & T7-tagged E.coli His/T7 Glu22~Leu275 (Accession # Q9QXT5)
Rat EGFL7-2027R Recombinant Rat EGFL7 Protein Mammalian Cell His
Rat EGFL7-1684R-B Recombinant Rat EGFL7 Protein Pre-coupled Magnetic Beads HEK293
Rat EGFL7-1684R Recombinant Rat EGFL7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EGFL7-1395R Recombinant Rhesus monkey EGFL7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EGFL7-1220R Recombinant Rhesus Macaque EGFL7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EGFL7-1220R-B Recombinant Rhesus Macaque EGFL7 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EGFL7-3802Z Recombinant Zebrafish EGFL7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EGFL7 Related Articles
  • EGFL7 Related Research Area

EGFL7 involved in several pathways and played different roles in them. We selected most pathways EGFL7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EGFL7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

EGFL7 has several biochemical functions, for example, Notch binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EGFL7 itself. We selected most functions EGFL7 had, and list some proteins which have the same functions with EGFL7. You can find most of the proteins on our site.

Function Related Protein
Notch bindingAAK1;JAG2B;GALNT11;JAG1A;ADAM17;JAG2;EGFL7;JAG1;NOTCH4
calcium ion bindingSLC25A12;LTBP2;PLCD1;MAN1B1;FAT3A;EFCAB7;AKR1C1;PNLIPRP1;JAG1A

EGFL7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EGFL7 here. Most of them are supplied by our site. Hope this information will be useful for your research of EGFL7.

LMP1; ul31_ebvb9; proS; katG; GFI1B; q81sn0_bacan; mrcA; hscA; SMARCD1; q9wmx2-pro_0000037541; Cenpe; Eef1a1; Smn1; CLTC; LOXL2

Zhang, JH; Vernes, JM; et al. Real-time immuno-polymerase chain reaction in a 384-well format: Detection of vascular endothelial growth factor and epidermal growth factor-like domain 7. ANALYTICAL BIOCHEMISTRY 463:61-66(2014).
Poissonnier, L; Villain, G; et al. Egfl7 Is Differentially Expressed in Arteries and Veins during Retinal Vascular Development. PLOS ONE 9:-(2014).
  • Q&As
  • Reviews

Q&As (5)

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In what ways can EGFL7 be targeted for therapeutic interventions? 07/11/2021

Therapeutic interventions may involve targeting EGFL7 to modulate angiogenesis. This could be achieved through the development of drugs or therapies that either inhibit or enhance EGFL7 activity, depending on the clinical context.

How does EGFL7 interact with other proteins in the angiogenic pathway? 07/09/2020

EGFL7 interacts with various proteins involved in the angiogenic pathway, including growth factors and receptors. Understanding these interactions is essential for deciphering its role in angiogenesis.

Can EGFL7 be used as a prognostic marker in cancer patients? 07/07/2019

Some research suggests that EGFL7 expression levels may have prognostic value in predicting outcomes for cancer patients. Higher or lower expression levels could be indicative of disease severity or response to treatment.

How is EGFL7 expression regulated in normal and pathological conditions? 01/13/2017

The regulation of EGFL7 expression is complex and varies in different conditions. Understanding the regulatory mechanisms is crucial for developing targeted therapies that modulate EGFL7 expression appropriately.

Is EGFL7 targeted in any existing therapies? 08/13/2016

As of now, there are no widely accepted therapies specifically targeting EGFL7. However, ongoing research may lead to the development of targeted therapies in the future.

Customer Reviews (3)

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Reviews
08/18/2022

    These resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.

    11/01/2020

      Their collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.

      07/28/2017

        The manufacturer's support is crucial for researchers using EGFL7 protein in trials.

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