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ELMO1

  • Official Full Name

    engulfment and cell motility 1

  • Overview

    This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  • Synonyms

    ELMO1; engulfment and cell motility 1; CED12; CED-12; ELMO-1; engulfment and cell motility protein 1; ced-12 homolog 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ELMO1-3251H Recombinant Human ELMO1 Protein, GST-tagged Wheat Germ GST
Human ELMO1-6622HCL Recombinant Human ELMO1 293 Cell Lysate HEK293 N/A
Human ELMO1-6623HCL Recombinant Human ELMO1 293 Cell Lysate HEK293 N/A
Human ELMO1-4380H Recombinant Human ELMO1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ELMO1-1420H Recombinant Human ELMO1 Protein, His-tagged E.coli N-His Arg471-Asn727
Human ELMO1-4359HF Recombinant Full Length Human ELMO1 Protein, GST-tagged In Vitro Cell Free System GST 727 amino acids
Mouse ELMO1-5139M Recombinant Mouse ELMO1 Protein Mammalian Cell His
Mouse ELMO1-2743M-B Recombinant Mouse ELMO1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Elmo1-994M Recombinant Mouse Elmo1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse ELMO1-2743M Recombinant Mouse ELMO1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ELMO1-1445R Recombinant Rhesus monkey ELMO1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ELMO1-1269R-B Recombinant Rhesus Macaque ELMO1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ELMO1-1269R Recombinant Rhesus Macaque ELMO1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ELMO1-12317Z Recombinant Zebrafish ELMO1 Mammalian Cell His
Chicken ELMO1-2677C Recombinant Chicken ELMO1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ELMO1 Related Articles
  • ELMO1 Related Signal Pathway

ELMO1 involved in several pathways and played different roles in them. We selected most pathways ELMO1 participated on our site, such as Chemokine signaling pathway, Bacterial invasion of epithelial cells, Shigellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELMO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chemokine signaling pathwayGNB4;XCL2;ROCK1;GNAI3;AKT2;HRAS;PLCB4;SHC3;PIK3CB
Bacterial invasion of epithelial cellsCDC42;PTK2;WAS;CRK;FN1;SHC4;ARPC5;ITGB1;CTNNA1
ShigellosisHCLS1;ABL1;WASL;IKBKG;MAPK11;PFN3;PFN1;CTTN;VCL

ELMO1 has several biochemical functions, for example, SH3 domain binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELMO1 itself. We selected most functions ELMO1 had, and list some proteins which have the same functions with ELMO1. You can find most of the proteins on our site.

Function Related Protein
SH3 domain bindingQK;SHANK2;KHDRBS2;INPPL1B;PLSCR1;GRIK5;WIPF3;RAD9;SH3BP1
protein bindingEPB41L1;LAMP1;ADH1A;SCAND1;PFKFB2;UCP3;PHB2;NMB;TAGLN2

ELMO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELMO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELMO1.

DOCK1; RAC1

Munir, S; Rahman, SB; et al. Association analysis of GWAS and candidate gene loci in a Pakistani population with psoriasis. MOLECULAR IMMUNOLOGY 64:190-194(2015).
Abu-Thuraia, A; Gauthier, R; et al. Axl Phosphorylates Elmo Scaffold Proteins To Promote Rac Activation and Cell Invasion. MOLECULAR AND CELLULAR BIOLOGY 35:76-87(2015).
  • Q&As
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