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EMG1

  • Official Full Name

    EMG1 nucleolar protein homolog (S. cerevisiae)

  • Overview

    This gene encodes an essential, conserved eukaryotic protein involved in ribosome biogenesis. In yeast, the related protein is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome.
  • Synonyms

    EMG1; EMG1 nucleolar protein homolog (S. cerevisiae); ribosomal RNA small subunit methyltransferase NEP1; C2F; Grcc2f; NEP1; 18S rRNA (pseudouridine-N1-)-methyltransferase NEP1; 18S rRNA Psi1248 methyltransferase; C2f protein; EMG 1; EMG1 nucleolar protein homolog (S cerevisiae); essential for mitotic growth 1; FLJ60792; NEP1_HUMAN; Nucleolar protein EMG1 homolog; Protein C2f; Ribosome biogenesis protein NEP1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EMG1-6938H Recombinant Human EMG1 Nucleolar Protein Homolog(S. cerevisiae), His-tagged E.coli His 1-244aa
Human EMG1-3277H Recombinant Human EMG1 Protein, GST-tagged Wheat Germ GST
Human EMG1-6611HCL Recombinant Human EMG1 293 Cell Lysate HEK293 N/A
Human EMG1-4242HF Recombinant Full Length Human EMG1 Protein, GST-tagged In Vitro Cell Free System GST 244 amino acids
Human EMG1-2331H Recombinant Human EMG1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse EMG1-5173M Recombinant Mouse EMG1 Protein Mammalian Cell His
Mouse Emg1-1058M Recombinant Mouse Emg1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse EMG1-2770M-B Recombinant Mouse EMG1 Protein Pre-coupled Magnetic Beads HEK293
Mouse EMG1-2770M Recombinant Mouse EMG1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EMG1-1463R Recombinant Rhesus monkey EMG1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EMG1-1288R Recombinant Rhesus Macaque EMG1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EMG1-1288R-B Recombinant Rhesus Macaque EMG1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EMG1-3766Z Recombinant Zebrafish EMG1 Mammalian Cell His
Chicken EMG1-5339C Recombinant Chicken EMG1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EMG1 Related Articles

EMG1 involved in several pathways and played different roles in them. We selected most pathways EMG1 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with EMG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ribosome biogenesis in eukaryotesEFTUD1;GNL3;POP5;RRP7A;MPHOSPH10;NHP2L1A;PWP2;RPP38;NXT1

EMG1 has several biochemical functions, for example, RNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMG1 itself. We selected most functions EMG1 had, and list some proteins which have the same functions with EMG1. You can find most of the proteins on our site.

Function Related Protein
RNA bindingSFSWAP;RPS3A;TROVE2;PUF60B;ZFR;DIMT1;PAPOLG;ACO1;RPL7
poly(A) RNA bindingRBFOX2;PRDX1;SARS2;C1orf35;R3HDM2;ZFC3H1;FARSA;CCDC9;PRMT1
protein bindingHTR6;SHFM1;DNMT3L;KLC3;P2RY6;FKBP2;HIST1H1A;NOP58;CHMP1A
rRNA (pseudouridine) methyltransferase activity
rRNA bindingDIEXF;RPS9;PPAN;RPL9;RPS5;RPS4Y2;ERI1;NOL12;ANG

EMG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EMG1.

FAM74A4; ANXA3; CTSE; HIVEP1; PSME1; KHDRBS1; NAT6; SLC25A38; PSMB7; ssrna_ug

Sondalle, SB; Baserga, SJ; et al. Human diseases of the SSU processome. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1842:758-764(2014).
Peifer, C; Sharma, S; et al. Yeast Rrp8p, a novel methyltransferase responsible for m(1)A 645 base modification of 25S rRNA. NUCLEIC ACIDS RESEARCH 41:1151-1163(2013).
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