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EPN1

  • Official Full Name

    epsin 1

  • Overview

    The protein encoded by this gene binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    EPN1; epsin 1; epsin-1; EH domain binding mitotic phosphoprotein; EPN 1; EPS 15 interacting protein 1; EPS-15-interacting protein 1; EH domain-binding mitotic phosphoprotein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EPN1-3415H Recombinant Human EPN1 Protein, GST-tagged Wheat Germ GST
Human EPN1-6581HCL Recombinant Human EPN1 293 Cell Lysate HEK293 N/A
Human EPN1-4628H Recombinant Human EPN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EPN1-1633H Recombinant Human EPN1 protein, His-tagged E.coli His Pro279~Gly437 (Accession # Q9Y6I3)
Human EPN1-4391HF Recombinant Full Length Human EPN1 Protein, GST-tagged In Vitro Cell Free System GST 550 amino acids
Human EPN1-2731H Recombinant Human EPN1 Protein (Pro279-Gly437), His tagged E.coli His Pro279-Gly437
Mouse EPN1-5257M Recombinant Mouse EPN1 Protein Mammalian Cell His
Mouse EPN1-2823M Recombinant Mouse EPN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Epn1-962M Recombinant Mouse Epn1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse EPN1-2823M-B Recombinant Mouse EPN1 Protein Pre-coupled Magnetic Beads HEK293
Rat EPN1-2125R Recombinant Rat EPN1 Protein Mammalian Cell His
Rat EPN1-1782R Recombinant Rat EPN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat EPN1-1782R-B Recombinant Rat EPN1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EPN1-12541Z Recombinant Zebrafish EPN1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EPN1 Related Articles

EPN1 involved in several pathways and played different roles in them. We selected most pathways EPN1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisGRK1B;VPS45;CAPZA1B;CBLC;BF1;RAB7;CYTH4B;ADRB3;EPS15

EPN1 has several biochemical functions, for example, ion channel binding, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPN1 itself. We selected most functions EPN1 had, and list some proteins which have the same functions with EPN1. You can find most of the proteins on our site.

Function Related Protein
ion channel bindingKCNQ1;CALM3;PHPT1;ACTN2;CDH5;AKAP9;RIMS1;PKP2;KCND3
lipid bindingSEC14L3;BPIFA3;ACOT12;SNX27;TRIP10A;STARD7;FABP12;IQSEC1;SH3GL3
protein bindingOXA1L;GNG12;FAM90A1;EPB42;FEZ1;PAPD4;SNTA1;RBM25;TRPC2
transcription factor bindingZFPM2;DDIT3;NLRP3;HES1;APBB1;JUNBA;PBX2;CEBPG;MAPK9

EPN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPN1.

REPS2; DAZAP2; PLEKHB2; VCAM1; UBA1; EPS15; UBE2N; UBE2V1; Map3k1; LAPTM5; CRMP1; npr

Benhra, N; Vignaux, F; et al. Neuralized Promotes Basal to Apical Transcytosis of Delta in Epithelial Cells. MOLECULAR BIOLOGY OF THE CELL 21:2078-2086(2010).
Jakobsson, J; Gad, H; et al. Role of epsin 1 in synaptic vesicle endocytosis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105:6445-6450(2008).
Khanna, R; Li, Q; et al. 'Fractional Recovery' Analysis of a Presynaptic Synaptotagmin 1-Anchored Endocytic Protein Complex. PLOS ONE 1:-(2006).
Han, ZZ; Karatan, E; et al. Accelerated screening of phage-display output with alkaline phosphatase fusions. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 7:55-62(2004).
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