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ERC1

  • Official Full Name

    ELKS/RAB6-interacting/CAST family member 1

  • Overview

    ERC1, an acronym named for previous protein names ELKS , RAB6IP2 and CAST, is a RIM-binding protein that plays a role in neurotransmitter release and general membrane trafficking in other cell types. Interaction with the GTP-binding protein Rab6 suggests
  • Synonyms

    ERC1; ELKS/RAB6-interacting/CAST family member 1; RAB6 interacting protein 2 , RAB6IP2; CAST2; ELKS; KIAA1081; MGC12974; RAB6 interacting protein 2; Rab6-interacting protein 2; RAB6IP2; FLJ31750;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ERC1-3453H Recombinant Human ERC1 Protein, GST-tagged Wheat Germ GST
Human ERC1-12519H Recombinant Human ERC1, His-tagged E.coli His C-term-132a.a.
Human ERC1-1024HCL Recombinant Human ERC1 cell lysate N/A
Human ERC1-4087H Recombinant Human ERC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ERC1-2115H Recombinant Human ERC1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ERC1-860H-B Recombinant Human ERC1 Protein Pre-coupled Magnetic Beads HEK293
Human ERC1-806HFL Recombinant Full Length Human ERC1 Protein, C-Flag-tagged Mammalian cells Flag
Human ERC1-4526HF Recombinant Full Length Human ERC1 Protein, GST-tagged In Vitro Cell Free System GST 91 amino acids
Human ERC1-860H Recombinant Human ERC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Erc1-494M Recombinant Mouse Erc1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat ERC1-2135R Recombinant Rat ERC1 Protein Mammalian Cell His
Rat ERC1-1792R Recombinant Rat ERC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ERC1-1792R-B Recombinant Rat ERC1 Protein Pre-coupled Magnetic Beads HEK293
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RFL21286SF Recombinant Full Length Saccharomyces Cerevisiae Ethionine Resistance-Conferring Protein 1(Erc1) Protein, His-Tagged E.coli expression system His Full Length (1-581)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ERC1 Related Articles

ERC1 involved in several pathways and played different roles in them. We selected most pathways ERC1 participated on our site, such as NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
NF-kappa B signaling pathwayLYN;LTBR;CD40;PTGS2;CFLAR;BCL2A1A;PLCG2;BTK;CXCL12

ERC1 has several biochemical functions, for example, PDZ domain binding, Rab GTPase binding, leucine zipper domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERC1 itself. We selected most functions ERC1 had, and list some proteins which have the same functions with ERC1. You can find most of the proteins on our site.

Function Related Protein
PDZ domain bindingSLC9A3;GIPC1;SNTB1;GRID2;PROSAPIP1;LIN7B;KIDINS220B;FZD3;DOCK4
Rab GTPase bindingRUSC2;ATP6AP1;RAB11FIP1;MYO5A;ANXA2;MLPHB;ANKRD27;ALS2;DENND5A
leucine zipper domain bindingMKL1;PAWR;KCNA3;DAPK3;ATF4;NRL;DDIT3;ERC1;CRX
protein bindingPRR16;ZNF317;CCDC28B;WNT3A;PPP1R37;KCNG3;CALM1;FAM168A;RPL7A

ERC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERC1.

YWHAG; PARP2; NR4A1; PHB; SMAD2; TWF2; KBTBD7; Ckap5; a0jp85; DVL2; SLC16A6; MYC; MAPK4; Kif4; Actb; KIF23; STK4; MAPRE1; CEP135

Huijbers, MG; Lipka, AF; et al. Antibodies to active zone protein ERC1 in Lambert-Eaton myasthenic syndrome. HUMAN IMMUNOLOGY 74:849-851(2013).
Billings, SE; Clarke, GL; et al. ELKS1 and Ca2+ channel subunit beta 4 interact and colocalize at cerebellar synapses. NEUROREPORT 23:49-54(2012).
  • Q&As
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