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HSD17B8

  • Official Full Name

    hydroxysteroid (17-beta) dehydrogenase 8

  • Overview

    Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) as
  • Synonyms

    HSD17B8; hydroxysteroid (17-beta) dehydrogenase 8; FabG (beta ketoacyl [acyl carrier protein] reductase, E coli) like (E. coli) , FABGL; estradiol 17-beta-dehydrogenase 8; D6S2245E; H2 KE6; HKE6; KE6; RING2; SDR30C1; short chain dehydrogenase/reductase fa;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSD17B8-13964H Recombinant Human HSD17B8, GST-tagged E.coli GST 1-261a.a.
Human HSD17B8-29342TH Recombinant Human HSD17B8, His-tagged E.coli His 261 amino acids
Human HSD17B8-5076H Recombinant Human HSD17B8 Protein, GST-tagged Wheat Germ GST
Human HSD17B8-3499H Recombinant Human HSD17B8, His-tagged E.coli His
Human HSD17B8-5371HCL Recombinant Human HSD17B8 293 Cell Lysate HEK293 N/A
Human HSD17B8-1109H Recombinant Human HSD17B8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HSD17B8-3881HF Recombinant Full Length Human HSD17B8 Protein, GST-tagged In Vitro Cell Free System GST 261 amino acids
Human HSD17B8-1069HFL Recombinant Full Length Human HSD17B8 Protein, C-Flag-tagged Mammalian cells Flag
Human HSD17B8-1109H-B Recombinant Human HSD17B8 Protein Pre-coupled Magnetic Beads HEK293
Rat HSD17B8-2931R Recombinant Rat HSD17B8 Protein Mammalian Cell His
Rat HSD17B8-2586R-B Recombinant Rat HSD17B8 Protein Pre-coupled Magnetic Beads HEK293
Rat HSD17B8-2586R Recombinant Rat HSD17B8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HSD17B8-603C Recombinant Cynomolgus HSD17B8 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey HSD17B8-349C Recombinant Cynomolgus Monkey HSD17B8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HSD17B8-349C-B Recombinant Cynomolgus Monkey HSD17B8 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HSD17B8-2157R Recombinant Rhesus monkey HSD17B8 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HSD17B8-1978R Recombinant Rhesus Macaque HSD17B8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HSD17B8-1978R-B Recombinant Rhesus Macaque HSD17B8 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HSD17B8-1393Z Recombinant Zebrafish HSD17B8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HSD17B8 Related Articles

HSD17B8 involved in several pathways and played different roles in them. We selected most pathways HSD17B8 participated on our site, such as Steroid hormone biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSD17B8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Steroid hormone biosynthesisHSD17B12B;CYP2D10;HSD17B12;SRD5A2A;UGT1AB;PPP1R2;CYP3A41B;HSD3B6;CYP3A25
Metabolic pathwaysCYP2A12;KL;NDUFA9A;NDUFA10;GLCEB;GALCB;CYP2C18;NT5E;ARG1

HSD17B8 has several biochemical functions, for example, 3-hydroxyacyl-CoA dehydrogenase activity, estradiol 17-beta-dehydrogenase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSD17B8 itself. We selected most functions HSD17B8 had, and list some proteins which have the same functions with HSD17B8. You can find most of the proteins on our site.

Function Related Protein
3-hydroxyacyl-CoA dehydrogenase activityHADHA;HSD17B8;HSD17B4;HADHAB;HADHB;EHHADH;HADHAA;H2-KE6;HADH
estradiol 17-beta-dehydrogenase activityAKR1C6;RDH8;HSD17B14;HSD17B10;HSD17B8;AKR1B15;HSD17B7;HSD17B2;H2-KE6
protein bindingSYTL1;DGKZ;GABBR2;BDKRB1;ZBTB8A;PSENEN;GRAP;BIRC3;ATXN3
testosterone dehydrogenase (NAD+) activityHSD17B1;DHRS9;H2-KE6;HSD17B2;AKR1C3;HSD17B6;HSD17B8

HSD17B8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSD17B8 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSD17B8.

ssrna_ac

Yang, FQ; Priester, S; et al. Castration inhibits biliary proliferation induced by bile duct obstruction: novel role for the autocrine trophic effect of testosterone. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 301:G981-G991(2011).
Motohara, K; Tashiro, H; et al. Immunohistochemical analysis of 17 beta-hydroxysteroid dehydrogenase isozymes in human ovarian surface epithelium and epithelial ovarian carcinoma. MEDICAL MOLECULAR MORPHOLOGY 43:197-203(2010).
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