fbxo27
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  • Official Full Name
  • F-box protein 27
  • Background
  • Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
  • Synonyms
  • FBXO27; F-box protein 27; F box only protein 27; F-box only protein 27; Fbg5; Fbx27; F-box G-domain protein 5; F-box protein FBG5; F-box/G-domain protein 5
Cat.#:FBXO27-3925HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FBXO27 Protein, GST-tagged
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Cat.#:FBXO27-5739MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FBXO27 Protein
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Cat.#:FBXO27-518CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FBXO27 Protein, His-tagged
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Cat.#:FBXO27-6302HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FBXO27 293 Cell Lysate
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Involved Pathway

FBXO27 involved in several pathways and played different roles in them. We selected most pathways FBXO27 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
ASB8; LRR1; LRRC41; UBE2V1; ITK; SEC23A; KIF2C; LILRB1; NRG4; LRSAM1
Antigen processing: Ubiquitination &
RNF138; UBE2L6; SPSB2; TRAF7; VPRBP; RNF25; TRIM50; PJA1; FBXO44; LTN1
Proteasome degradation
NPEPPS; RNF6; TRIM11; RNF41; LRSAM1; ASB18; GAN; RNF4; DTX3L; UBA5
Class I MHC mediated antigen processing &
ASB7; RNF14; FBXO27; CMTM2A; UBR2; ASB4; NPEPPS; LTN1; GAN; TRIM41
presentation
BLMH; RBCK1; UBE2F; GAN; UBE2J2; UBE2L6; RNF6; TRAF7; ASB7; CYBB
Immune System
BAIAP2; SEC61B; TRIM2; IFIT11; IFIT10; TRIM63; CD96; IFITM3; CLEC2G; UBE2F

Protein Function

FBXO27 has several biochemical functions, for example, glycoprotein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO27 itself. We selected most functions FBXO27 had, and list some proteins which have the same functions with FBXO27. You can find most of the proteins on our site.
Function
Related Protein
Function glycoprotein binding
Related Protein CDH1; SDCBP; DNAJC5; LMAN2; SERPINA1D; EDEM1; THBS1; SELP; FGFR1; FLNA
Function protein binding
Related Protein FLT4; FAM161A; PPP4R2; TTLL6; RBPJ; TERT; HDDC2; GGN; CDX4; CNEP1R1

Interacting Protein

FBXO27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO27 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO27.
HSP90AB1