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FDPS

  • Official Full Name

    cross-linked fibrin degradation products

  • Overview

    During blood coagulation, fibrinogen is converted to fibrin by the activation of thrombin. The resulting fibrin monomers polymerize to form a soluble gel of non-cross-linked fibrin. This fibrin gel is then converted to cross-linked fibrin by thrombin activated Factor XIII to form an insoluble fibrin clot. Production of plasmin, the major clot-lysing enzyme, is triggered when a fibrin clot is formed. Fibrinogen and fibrin are both cleaved by the fibrinolytic enzyme plasmin to yield degradation products, but only degradation products from crosslinked fibrin contain D-Dimer. Therefore, cross-linked fibrin degradation products (XL-FDP) are a specific marker of fibrinolysis.
  • Synonyms

    FDPs; Fibrin Degradation Products; Geranyltranstransferase; (2E; 6E)-farnesyl diphosphate synthase; dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl diphosphate synthetase; Farnesyl pyrophosphate synthase; Farnesyl pyrophosphate synthetase; Fdps; FPP synthase; FPP synthetase; FPPS; FPS;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FDPS-1150H Recombinant Human FDPS protein, His & GST-tagged E.coli His/GST Met1~Lys419 (Accession # P14324)
Human FDPS-517H Recombinant Human FDPS Protein, His-tagged E.coli His
Human FDPS-28480TH Recombinant Human FDPS Wheat Germ N/A 100 amino acids
Human FDPS-12834H Recombinant Human FDPS, GST-tagged E.coli GST 68-419a.a.
Human FDPS-615HCL Recombinant Human FDPS cell lysate N/A
Human FDPS-4775HF Recombinant Full Length Human FDPS Protein, GST-tagged In Vitro Cell Free System GST 419 amino acids
Human FDPS-4058H Recombinant Human FDPS Protein, GST-tagged Wheat Germ GST
Human FDPS-2895H Recombinant Human FDPS protein, His-SUMO-tagged E.coli His-SUMO 1-419aa
Mouse FDPS-5804M Recombinant Mouse FDPS Protein Mammalian Cell His
Mouse Fdps-1001M Recombinant Mouse Fdps protein, His-tagged E.coli His Met1-Lys353
Mouse FDPS-3202M Recombinant Mouse FDPS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FDPS-3202M-B Recombinant Mouse FDPS Protein Pre-coupled Magnetic Beads HEK293
Rat Fdps-1151R Recombinant Rat Fdps protein, His & GST-tagged E.coli His/GST Met1~Lys353 (Accession # P05369)
Rat FDPS-2309R Recombinant Rat FDPS Protein Mammalian Cell His
Rat FDPS-1966R Recombinant Rat FDPS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FDPS-1966R-B Recombinant Rat FDPS Protein Pre-coupled Magnetic Beads HEK293
Zebrafish FDPS-3109Z Recombinant Zebrafish FDPS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FDPS Related Articles

FDPS involved in several pathways and played different roles in them. We selected most pathways FDPS participated on our site, such as Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with FDPS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Terpenoid backbone biosynthesisGGPS1;IDI2;DHDDS;HMGCRB;ACAT1;FNTB;PMVK;ICMT;MVDA
Metabolic pathwaysNANP;HSD3B4;ACADSB;LDHAL6A;PCYT1BA;PLA2G4C;ALPI.1;PAICS;RRM2B
Influenza AIL1B;MAPK13;IKBKB;NXT1;MAPK10;TNFRSF10B;NXF2;Ifna15;Ifna11
HTLV-I infectionWNT10B;BAX;VDAC2;WNT16;H2-Q10;TGFB3;HLA-C;FZD1;RB1

FDPS has several biochemical functions, for example, dimethylallyltranstransferase activity, geranyltranstransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FDPS itself. We selected most functions FDPS had, and list some proteins which have the same functions with FDPS. You can find most of the proteins on our site.

Function Related Protein
dimethylallyltranstransferase activityGGPS1;FDPS
geranyltranstransferase activityFDPS;GGPS1
metal ion bindingAOX4;ERI1;ZFP637;CYP2K22;ANKMY1;DDHD1;SP6;GM5077;ZNF609A
poly(A) RNA bindingRPS25;RPL24;LTA4H;UBFD1;LLPH;WDR3;NOM1;CCDC108;TXN

FDPS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FDPS here. Most of them are supplied by our site. Hope this information will be useful for your research of FDPS.

EIF4ENIF1; ATXN1; q81kq8_bacan; cydC; TSG101

Zhang, LW; McCabe, T; et al. An Anti-PCSK9 Antibody Reduces LDL-Cholesterol On Top Of A Statin And Suppresses Hepatocyte SREBP-Regulated Genes. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 8:310-327(2012).
Wada, H; Sakuragawa, N; et al. Are fibrin-related markers useful for the diagnosis of thrombosis?. SEMINARS IN THROMBOSIS AND HEMOSTASIS 34:33-38(2008).
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