FES
-
Official Full Name
feline sarcoma oncogene
-
Overview
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms. -
Synonyms
FES; feline sarcoma oncogene; feline sarcoma (Snyder Theilen) viral (v fes)/Fujinami avian sarcoma (PRCII) viral (v fps) oncogene homolog; tyrosine-protein kinase Fes/Fps; c fes/fps protein; FPS; Oncogene FES; feline sarcoma virus; p93c-fes; proto-oncogen;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Insect (sf21)
- Insect Cell
- Mammalian Cell
- Sf21
- Sf9 Insect Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|GST
- His|T7
- N/A
- No tag
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | FES-1404H | Active Recombinant Human FES, GST-tagged | Sf9 Insect Cell | GST | Full length | |
Human | FES-80H | Active Recombinant Human FES(2-end) Protein, N-His-tagged | Sf21 | His | 2-end | |
Human | FES-902H | Recombinant Human FES, His & GST tagged | Insect Cell | His/GST | ||
Human | FES-311H | Recombinant Human Feline Sarcoma Oncogene, GST-tagged, Active | Sf9 Insect Cell | GST | ||
Human | FES-606HCL | Recombinant Human FES cell lysate | Insect Cell | N/A | ||
Human | FES-3307H | Recombinant Human FES protein, His-tagged | E.coli | His | 125-390 aa | |
Human | FES-4078H | Recombinant Human FES Protein, GST-tagged | Wheat Germ | GST | ||
Human | FES-1322S | Recombinant Human FES Protein (I448-R822), His tagged | E.coli | His | I448-R822 | |
Human | FES-1627H | Recombinant Human FES protein, His & T7-tagged | E.coli | His/T7 | Leu509~Asn766 (Accession # P07332) | |
Human | FES-1506HF | Active Recombinant Full Length Human FES Protein, GST-tagged | Insect (sf21) | GST | 1-413, 416-822 | |
Human | FES-1321S | Recombinant Human FES Protein (I448-R822), Tag Free | E.coli | No tag | I448-R822 | |
Human | FES-4793HF | Recombinant Full Length Human FES Protein, GST-tagged | In Vitro Cell Free System | GST | 822 amino acids | |
Mouse | FES-5820M | Recombinant Mouse FES Protein | Mammalian Cell | His | ||
Mouse | Fes-1628M | Recombinant Mouse Fes protein, His & T7-tagged | E.coli | His/T7 | Asp510~Arg770 (Accession # P16879) | |
Mouse | FES-3212M-B | Recombinant Mouse FES Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | FES-3212M | Recombinant Mouse FES Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Zebrafish | FES-7883Z | Recombinant Zebrafish FES | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- FES Related Articles
- FES Related Research Area
FES involved in several pathways and played different roles in them. We selected most pathways FES participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with FES were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Axon guidance | EFNA4;EPHB4A;SPTBN1;DUSP7;PLXNA3;SEMA6C;ROBO1;RASGRP4;FGF8B |
FES has several biochemical functions, for example, ATP binding, immunoglobulin receptor binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FES itself. We selected most functions FES had, and list some proteins which have the same functions with FES. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | RENBP;CDC42BPA;LMTK3;UBE2E3;VRK1;PFKL;RPS6KA3B;CSNK1G2B;UBE1Y1 |
immunoglobulin receptor binding | FGR;IGLL1;IGKC;Ighg;Ighg2b;IgG3;IGLC2;CLEC4D;Ighg2a |
microtubule binding | RGS14;DPYSL5;NUSAP1;PRC1;KIF12;SERPINB1A;MAPRE3B;FTCD;MTAP7D3 |
non-membrane spanning protein tyrosine kinase activity | FGR;STK16;FRK;WEE1;SRMS;BAZ1B;PTK6;EIF2AK2;JAK2A |
phosphatidylinositol binding | GRB7;TNFAIP8L3;SNX27B;PIK3C2G;SNX1A;SEPT12;SGK3;ING2;TULP2 |
protein binding | KISS1;MAL;SMPDL3A;WAC;BSCL2;PHYH;UBXN2B;FLT1;NOX5 |
protein tyrosine kinase activity | JAK2A;RET;EGFRA;FER;TNK2;KIAA1804;EK1;JAK3;TTN |
FES has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FES here. Most of them are supplied by our site. Hope this information will be useful for your research of FES.
EZR; TERF1; MDFI; EGFR; MET; AR; KIT; NSF
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All FES Products
Required fields are marked with *
My Review for All FES Products
Required fields are marked with *