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FGD3

  • Official Full Name

    FYVE, RhoGEF and PH domain containing 3

  • Overview

    FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene.
  • Synonyms

    FGD3; FYVE, RhoGEF and PH domain containing 3; FGD1 family, member 3; FYVE, RhoGEF and PH domain-containing protein 3; FLJ00004; ZFYVE5; Faciogenital dysplasia 3; FYVE, RhoGEF and PH domain containing protein 3; Zinc finger FYVE domain containing protein 5; zinc finger FYVE domain-containing protein 5;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGD3-12859H Recombinant Human FGD3, GST-tagged E.coli GST C-term-156a.a.
Human FGD3-27710TH Recombinant Human FGD3, His-tagged E.coli His
Human FGD3-619HCL Recombinant Human FGD3 cell lysate N/A
Human FGD3-4090H Recombinant Human FGD3 Protein, GST-tagged Wheat Germ GST
Human FGD3-4789HF Recombinant Full Length Human FGD3 Protein, GST-tagged In Vitro Cell Free System GST 725 amino acids
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FGD3 Related Articles

FGD3 involved in several pathways and played different roles in them. We selected most pathways FGD3 participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of actin cytoskeletonARPC5A;RAC1;MSNA;MSN;PDGFC;ITGB7;IQGAP3;PAK7;Fgf15

FGD3 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGD3 itself. We selected most functions FGD3 had, and list some proteins which have the same functions with FGD3. You can find most of the proteins on our site.

Function Related Protein
Rho guanyl-nucleotide exchange factor activityECT2;ARHGEF18;ARHGEF6;ARHGEF3L;ITSN2A;C9orf100;FGD4A;ARHGEF7A;DCLRE1B
guanyl-nucleotide exchange factor activityRASGRP2;TBC1D10A;DOCK6;RAPGEF5B;SBF1;ARHGEF18;DENND6A;CHRM4;TAGAP
metal ion bindingABAT;PDE7B;ZFP13;PDE4D;TRIM35-1;ZFP804A;BTR02;MGAT4C;ENPP4
small GTPase bindingFGD3;TSC2;RNF152;ERRFI1;PEX5L;PEX5;FGD2;FGD5;FGD6

FGD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGD3.

pi3p

Yang, THO; Cheng, WY; et al. Breast Cancer Prognostic Biomarker Using Attractor Metagenes and the FGD3-SUSD3 Metagene. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 23:2850-2856(2014).
Vu, MMK; Jameson, NE; et al. Convergent Evolution of Adenosine Aptamers Spanning Bacterial, Human, and Random Sequences Revealed by Structure-Based Bioinformatics and Genomic SELEX. CHEMISTRY & BIOLOGY 19:1247-1254(2012).
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