fktn
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  • Official Full Name
  • fukutin
  • Background
  • The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.
  • Synonyms
  • FKTN; fukutin; FCMD, Fukuyama type congenital muscular dystrophy (fukutin); LGMD2M; CMD1X; FCMD; FKTN_HUMAN; Fukuyama type congenital muscular dystrophy protein; Fukuyama-type congenital muscular dystrophy protein; MDDGA4; MDDGB4; MDDGC4; MGC126857; MGC134944; MGC134945; MGC138243; OTTHUMP00000021841
Cat.#:FKTN-4016HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FKTN Protein, GST-tagged
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Cat.#:FKTN-12921HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FKTN, His-tagged
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Cat.#:FKTN-3822ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FKTN
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Cat.#:FKTN-6198HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FKTN 293 Cell Lysate
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Protein Function

FKTN has several biochemical functions, for example, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FKTN itself. We selected most functions FKTN had, and list some proteins which have the same functions with FKTN. You can find most of the proteins on our site.
Function
Related Protein
Function transferase activity
Related Protein SMG1; KITA; CD38; NTRK3A; MRPL2; PRDM6; MIBP; PFKFB2A; UGT5A5; ACVR1L

FKTN Related Articles

Humphrey, EL; Lacey, E; et al. A new monoclonal antibody DAG-6F4 against human alpha-dystroglycan reveals reduced core protein in some, but not all, dystroglycanopathy patients. NEUROMUSCULAR DISORDERS 25:32-42(2015).
Fortunato, MJ; Ball, CE; et al. Development of Rabbit Monoclonal Antibodies for Detection of Alpha-Dystroglycan in Normal and Dystrophic Tissue. PLOS ONE 9:-(2014).