FMNL3
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Official Full Name
formin-like 3
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Overview
The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described. -
Synonyms
FMNL3; formin-like 3; formin-like protein 3; DKFZp762B245; MGC45819; WBP3; WW domain binding protein 3; WW domain-binding protein 3; formin homology 2 domain-containing protein 3; FHOD3; WBP-3; FLJ45265;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | FMNL3-659HCL | Recombinant Human FMNL3 cell lysate | N/A | |||
Human | FMNL3-4986HF | Recombinant Full Length Human FMNL3 Protein, GST-tagged | In Vitro Cell Free System | GST | 347 amino acids | |
Human | FMNL3-2435H | Recombinant Human FMNL3 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | FMNL3-4391H | Recombinant Human FMNL3 Protein, GST-tagged | Wheat Germ | GST | ||
Mouse | FMNL3-5936M | Recombinant Mouse FMNL3 Protein | Mammalian Cell | His | ||
Mouse | FMNL3-3288M-B | Recombinant Mouse FMNL3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | FMNL3-3288M | Recombinant Mouse FMNL3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | Fmnl3-3052M | Recombinant Mouse Fmnl3 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
- Involved Pathway
- Protein Function
- Interacting Protein
- FMNL3 Related Articles
FMNL3 involved in several pathways and played different roles in them. We selected most pathways FMNL3 participated on our site, such as Downregulation of ERBB2:ERBB3 signaling, Endocytosis, ErbB2/ErbB3 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with FMNL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Downregulation of ERBB2:ERBB3 signaling | NRG2A;FMNL3;RNF41 |
Endocytosis | RET;ZFYVE9;IST1;IGF1RA;ZFYVE27;GRK7;CYTH1A;ERBB4A;WASLB |
ErbB2/ErbB3 signaling events | CHRNE;DOCK7;RNF41;CHRNA1;FMNL3 |
Internalization of ErbB1 | ZFYVE28;SPRY2;FMNL3;RNF103-CHMP3;STAMBP |
Regulation of FZD by ubiquitination | FMNL3;RNF43;RSPO2;LGR6;LGR5;RSPO4;LGR4;RSPO1;ZNRF3 |
Signal Transduction | FSTL1A;GDI2;METAP2;OTUD7B;CSNK1G2;GPR18;HCRT;CRABP1B;DLC1 |
Signaling by ERBB2 | FMNL3;CUL5A |
Signaling by Wnt | PRICKLE1;TNKS;SRY;RNF146;LGR6;WLS;WNT8-2;USP34;RSPO3 |
FMNL3 has several biochemical functions, for example, SH3 domain binding, cysteine-type endopeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FMNL3 itself. We selected most functions FMNL3 had, and list some proteins which have the same functions with FMNL3. You can find most of the proteins on our site.
Function | Related Protein |
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SH3 domain binding | KHDRBS1;MAPK15;ENKUR;DNAJC6;FUT8;ILK;FMNL3;ADAM15;ARHGAP6 |
cysteine-type endopeptidase activity | CTSM;FAM49BA;CASPB;USP17L2;CTSH;PSD;USP20;ESPL1;USP30 |
protein binding | ATP6V1H;NT5C3B;PPAP2B;E2F1;PENK;CDPF1;PCM1;C12orf68;FBL |
ubiquitin-specific protease activity | UCHL1;USP2;USP51;USP33;OTUB2;USP2A;USP31;STAMBP;UFD1L |
FMNL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FMNL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FMNL3.
Dlg4; PRPF40A
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